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Mustopic (Tacrolimus)

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Mustopic is used with other medications to prevent rejection of a kidney, heart, or liver transplant. This medication belongs to a class of drugs known as immunosuppressants. It works by weakening your body's defense system (immune system) to help your body accept the new organ as if it were your own.

Other names for this medication:
Acroli, Crolim, Cromus, Mustopic, Olmis, Pangraf, Protopic, Seegraf, Tacloran, Tacrel, Tacrim, Tacroderm, Tacrograf, Tacrokid, Tacrolimus, Tacromus, Tacrotor, Tacrovate, Tacroz, Tacstead, Talimus, Tarcel, Techlomus, Topgraf, Triplibact, Vingraf

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Also known as: Tacrolimus


Mustopic (tacrolimus) weakens your body's immune system, to help keep it from "rejecting" a transplanted organ such as a kidney. Organ rejection happens when the immune system treats the new organ as an invader and attacks it.

Mustopic is a prescription medicine and is used together with other medicines to prevent your body from rejecting a heart, liver, lung, or kidney transplant.

Mustopic is supplied as oral capsules, granules for oral suspension, and as an injection for intravenous use.

Mustopic capsules and oral granules are immediate-release medicines and they are not the same as tacrolimus extended-release tablets or tacrolimus extended-release capsules. Your healthcare provider should decide what medicine is right for you.


A nurse or other trained health professional will give you this medicine in a hospital. It is given through a needle placed into one of your veins. Your doctor may let you stay for at least the first 30 minutes after the start of the infusion and at frequent intervals thereafter.

You will only receive this medicine for a few days. Then your doctor will switch you to the oral (by mouth) form of tacrolimus.

This medicine comes with a patient information insert and patient instructions. Read and follow the instructions carefully. Ask your doctor if you have any questions.

You should not eat grapefruit or drink grapefruit juice while you are receiving this medicine. Grapefruit and grapefruit juice will increase the amount of medicine in the body.

Detailed Mustopic dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Mustopic are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Avoid receiving a "live" vaccine. The vaccine may not work as well while you are using Mustopic. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (shingles).

Grapefruit may interact with tacrolimus and cause side effects. Avoid consuming grapefruit products.

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