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Mepride (Glimepiride)

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Mepride tells your pancreas to increase the amount of insulin it produces in your body. Insulin works to lower your blood sugar. Mepride lowers your blood sugar in about 2 to 3 hours after you take the medication. This is why it is important to take the medication with your largest meal of the day.

Other names for this medication:
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Also known as: Glimepiride


Mepride (glimepiride) is an oral diabetes medicine that helps control blood sugar levels.

Mepride is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. This medicine is not for treating type 1 diabetes.

Insulin or other diabetes medicines are sometimes used in combination with Mepride if needed.


Usual Adult Dose for Diabetes Type 2:

Initial dose: 1 to 2 mg orally once a day Maintenance dose: Increase in 1 or 2 mg increments no more frequently than every 1 to 2 weeks based on glycemic response Maximum dose: 8 mg per day Comments: -Administer with breakfast or first main meal of the day. -In patients who are at increased risk for hypoglycemia, start with 1 mg orally once a day and titrate slowly. -When patients are being transferred to this drug from a longer half-life sulfonylurea, monitor 1 to 2 weeks for overlapping drug effect. Use: As an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus.

Usual Geriatric Dose for Diabetes Type 2:

Initial dose: 1 mg orally once a day; titrate slowly and monitor closely

Usual Pediatric Dose for Diabetes Type 2:

Not recommended because of adverse effects on body weight and hypoglycemia.

Detailed Mepride dosage information


If you overdose Generic Mepride and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Mepride are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Mepride if you are allergic to glimepiride, sulphonamides, or if you have:

an allergy to sulfa drugs; or diabetic ketoacidosis (call your doctor for treatment).

To make sure Mepride is safe for you, tell your doctor if you have ever had:

heart disease; liver or kidney disease; or an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD).

Mepride may increase your risk of serious heart problems, but not treating your diabetes can also damage your heart and other organs. Talk to your doctor about the risks and benefits of this medicine.

Follow your doctor's instructions about using Mepride if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby. However, you may need to stop taking Mepride for a short time just before your due date.

Medications similar to glimepiride have caused severe hypoglycemia in newborn babies whose mothers used the medicine near the time of delivery. If you take glimepiride during pregnancy, stop taking this medicine at least 2 weeks before your due date.

If you breastfeed while taking glimepiride, call your doctor if your baby shows signs of hypoglycemia (extreme drowsiness, feeding problems, mottled skin, blue lips, feeling cold or jittery, or having a seizure).

Mepride is not approved for use by anyone younger than 18 years old.

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