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Amebidal (Metronidazole)
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Amebidal

Amebidal is an antibiotic and antiprotozoal medication. It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. It is effective for dracunculiasis, giardiasis, trichomoniasis, and amebiasis.

Other names for this medication:
Aldezole, Anabact, Anamet, Arilin, Bemetrazole, Camezol, Colpofilin, Dazotron, Emedal, Fladex, Flanizol, Flazole, Mecozol, Metrajil, Metris, Metrogyl, Metrosil, Metroson, Missilor, Molazol, Nidazea, Nidazyl, Nizole, Onida, Rosiced, Rupezol, Taremis, Venogyl, Vertisal

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Also known as: Metronidazole

Description

Metronidazole is used to treat bacterial infections in different areas of the body. The extended-release tablets are used to treat women with vaginal infections (bacterial vaginosis).

Metronidazole belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain metronidazole. It may not be specific to Amebidal. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

The capsules can be taken with or without food. If the medicine upsets your stomach, it is best to take it with a meal or snack.

The extended–release tablet must be taken without food, 1 hour before or 2 hours after a meal.

Swallow the extended-release tablet whole. Do not break, crush, or chew it.

To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. If you stop using this medicine too soon, your infection may return.

This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. Also, it is best to take the doses at evenly spaced times during the day. If you need help planning the best times to take your medicine, check with your doctor.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (capsules or tablets): For amebiasis infections: Adults—500 or 750 milligrams (mg) 3 times a day for 5 to 10 days. Children—Dose is based on body weight and must be determined by your doctor. The dose is usually 35 to 50 milligrams (mg) per kilogram (kg) of body weight per day, divided into 3 doses, for 10 days. For bacterial infections: Adults—Dose is based on body weight and must be determined by your doctor. The dose is usually 7.5 milligrams (mg) per kilogram (kg) of body weight every 6 hours for 7 to 10 days. Your doctor may increase your dose as needed. However, the dose is usually not more than 4000 mg per day. Children—Use and dose must be determined by your doctor. For trichomoniasis infections: Adults—The tablet can be given 3 different ways: as a single dose of 2 grams, as 1 gram 2 times a day for 1 day, or as 250 milligrams (mg) 3 times a day for 7 days. The capsule dose is 375 mg 2 times a day for 7 days. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): For bacterial vaginosis: Adults—750 milligrams (mg) once a day for 7 days. Children—Use and dose must be determined by your doctor.

Overdose

In cases of overdose in adults, the clinical symptoms are usually limited to nausea, vomiting, ataxia and slight disorientation. In a preterm newborn, no clinical or biological sign of toxicity developed.

There is no specific treatment for Amebidal overdose, Amebidal infusion should be discontinued. Patients should be treated symptomatically.

Storage

Store at room temperature below 25 degrees C (77 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amebidal are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies have not been performed on the relationship of age to the effects of metronidazole capsules and tablets in the pediatric population, except for the treatment of amebiasis. Safety and efficacy have not been established.

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of metronidazole extended-release tablets to treat bacterial vaginosis in teenage females, but should not be used before the start of menstruation.

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Sex, plasma lipoproteins, and atherosclerosis: prevailing assumptions and outstanding questions. The current data show that histologic alterations of subcutaneously implanted donor bronchial rings correlate with lung tissue biopsy scores based on the ISHLT working formulation. Exposure of monocytes to exogenous recombinant TNF (rTNF) selectively up-regulated DR alpha-mRNA but not DP or DQ alpha-mRNA. The latter is based on the premise that they recognize their weaknesses and seek remedial action accordingly. The GABA(A) receptor or GABAergic neurons are involved in the action of many of these hormones. Physical and histological behavior of a new injectable collagen (GAX 65) implanted into the submucosal space of the mini-pig bladder. Restarting of ITD sensitivity at 300 pulsess by introducing a single reduced interpulse interval was not observed. Solophenols B-D and solomonin: new prenylated polyphenols isolated from propolis collected from the Solomon Islands and their antibacterial activity.

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Aspiration of dead space allows normocapnic ventilation at low tidal volumes in man. The amount of estradiol leaving the liver following oral administration is substantially less than that which enters it through the portal vein. In facilities without the resources required to undertake long-term audits for all the high risk infants they graduate, these growth parameters may also be used as selection criteria for those meriting such follow up reducing costs. The temperature rise can be due to the friction between the edges of the defect and/or the plastic deformation around the defect. The third experiment concentrated on the influence of nutrition level. In conclusion, the stem of mobile bearing tibial components should be cemented to provide increased micromotion and earlier loosening. Thus EMG biofeedback training can be accomplished and exercised without disruption of ongoing mental activity. We have previously shown that using computerized alerts and academic detailing results in significant improvement in physician adherence to secondary prevention guidelines for acute myocardial infarction. Of the 8 patients with underlying anomalies 6 underwent voiding cystourethrography and 6 underwent excretory urography, and the diagnosis was established in 6 (100 per cent) and 4 (67 per cent), respectively. Due to its capacity to express somatostatin receptors, it can be detected in vivo with 111In-pentetreotide scintigraphy (Ostreoscan).

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Microbiologic evaluation of canine urine: direct microscopic examination and preservation of specimen quality for culture. The results suggest that dobutamine differs from other catecholamines in its mode of action and that its cardiovascular actions may be mediated in part through an indirect action on adrenoceptors. Pyoderma gangrenosum with myelodysplastic syndrome treated with analogous bone marrow transplantation. Subsequent stamping on the amine-terminated surface results in the selective transfer of the aligned nanowires with a controlled length corresponding to the width of the relief region of the polymer stamp. Colonies that produce female sexuals are always composed of highly related females, while colonies that produce males often show low levels of nestmate relatedness. These results provide a mechanism for specificity and regulation of PKCzeta-targeted phosphorylation. The amino acid sequence of this peptide is YPPKPENPGEDAPPEELAKYYSALRHYINLITRQRY-NH2. Role of adenosine in airway inflammation in an allergic mouse model of asthma. It is a very rare disease and theoretically, it can present de novo or progress from an antecedent Langerhans cell histiocytosis (LCH). Proteomic identification of small, copper-responsive proteins in germinating embryos of Oryza sativa.

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The map position of murZ (69.3 min) differed from that determined for murA (90 min), a gene which had been previously proposed to encode the same activity (P.S. Use of hospital data for Safe Motherhood programmes in south Kalimantan, Indonesia. Conjunctions between motion and disparity are encoded with the same spatial resolution as disparity alone. Anterior cruciate ligament reconstruction associated with extra-articular tenodesis: A prospective clinical and radiographic evaluation with 10- to 13-year follow-up. Synergy with rifampin was demonstrated with both erythromycin and clindamycin. The future role of the nurse as perceived by a member of the medical profession. The effect of luteal phase supplementation of micronized oral progesterone, 200 mg daily, on the serum levels of endometrial secretory placental protein 14 (PP14)/beta-lactoglobulin homologue was studied in a double blind/cross-over fashion on five infertile women with apparently normal ovulatory cycles. Because 11beta-HSD-1 can function as a reductase, the expression of 11beta-HSD-1 in human syncytiotrophoblast would be consistent with the ability of this tissue to convert cortisone to cortisol and provide a means by which transplacental transport of cortisol could regulate the fetal pituitary adrenocortical axis in the human, as recently shown experimentally in the non-human primate baboon model. Literature mining of protein-residue associations with graph rules learned through distant supervision.

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Protective immunity to the group A Streptococcus may be only strain specific. Transformants expressing sense/antisense RNA of MCNA exhibited significant reductions in mycelial growth, conidiation, appressorium formation, and pathogenicity. Spring viremia of carp virus (SVCV) causes a highly contagious and serious disease of freshwater cyprinid fishes, generating significant economic and ecological impacts throughout the world. Immunocytochemistry and morphometric analysis showed that the antibody was taken up by neurons with the size and stereotaxic distribution of vasopressin-producing neurons. Based on the current literature, significant extravasation is a common finding during the first 5 to 8 postoperative days. The extensibility of the system is achieved by the use of open methods and protocols, so new components can be easily added.

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Combinatorial regulation of tissue specification by GATA and FOG factors. Low 25OHD level predicted mortality more weakly, mainly for the first 3 years of the follow-up, and was strongly influenced by the confounding variables. Our proposed technique with laparoscopic interruption or coagulation of deferential veins when proved by CDUS to be refluxing may allow successful treatment for most varicoceles. Evidence-based clinical practice guidelines issued by scientific societies reflect these new developments. The genotypic characteristics of 12 MRSA samples isolated from 11 neonatal patients transferred from 2 primary care obstetrics clinics to a tertiary care hospital were investigated by means of multilocus sequence typing, spa (staphylococcal protein A) typing, and SCCmec typing. A 10-year (1993-2002) retrospective review of the cytopathology slides from the Division of Cytopathology, Department of Pathology, Long Island Jewish Medical Center, New Hyde Park, New York, identified a total of 97 consecutive salivary gland FNAB cases that microscopically were interpreted as representing cystic lesions. These studies suggest a direct role for MMR proteins in recognizing and signalling DNA damage responses that is independent of the MMR catalytic repair process. The expanded hexanucleotide repeat is only identified in our familial FTD patients but not in patients with predominant parkinsonism. The metabolomics with a highly multiplexed and efficient manner is a challenging goal in nephrology.

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The aim of the study was to reveal the location and clinical characteristics of gangliosidosis in pediatric neurology. Females reported more child and adult high-betrayal trauma (i.e., trauma perpetrated by someone close) than did males. DNA analysis revealed low amounts of a 4.8 kb mtDNA deletion but with no differences in frequency or quantity in the control and experimental groups. Ten studies (4 cohort studies and 6 case-control studies) met the inclusion criteria of the meta-analysis, nine of which contributing to the main analysis (dose-response analysis, no lag time). A testis-sparing procedure was performed for 5 epidermoid cysts, the Sertoli cell tumor and the simple intratesticular cyst. Multiple logistic regression analysis was used to adjust for confounding between variables. Participation of the anaerobia flora in peritonitis and localized peritoneal abscess. Intrathoracic light-assisted anterior limited thoracotomy in lung cancer surgery.

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The data enable the determination of the photoconversion achievable in the solid state as well as some assessment of the influence of the deposition method on the photoconversion. Although there have been no radical breakthroughs in the treatment of fungal keratitis from the point of view of new antifungal agents, a better understanding of the epidemiology and pathology of the disease, as well as the drugs available and the appropriate surgical interventions, has led to an improvement in the management of this difficult corneal infection. Antioxidants counteract lipopolysaccharide-triggered alterations of human colonic smooth muscle cells. A new version of the Farnsworth lantern, the Optec 900, is now produced because the original version is no longer manufactured. Coagulation factor concentrates did not improve platelet interactions in the Impact R, but did have favourable effects on coagulation parameters measured by TG and TEM. rickettsii in nature, and that the CF test is generally unsuitable for serological diagnosis of this organism in birds. After transplantation, the mice were observed by slit lamp biomicroscopy on a weekly basis and graded for signs of graft rejection and delayed-type hypersensitivity (DTH) and cytotoxic T lymphocyte (CTL) responses to donor alloantigens assessed at selected times after grafting. The aim of this study is to gain a better understanding of the perception of hikikomori amongst health-related students and professionals and to explore possible psychiatric conditions underlying hikikomori.

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Diagnostic strategies for evaluation and prognosticating the outcome of jaundice among patients with cholestasis caused by neoplastic diseases of the hepatobiliary system and the pancreas. A systematic literature search (PubMed, EMBASE, Science Citation Index, Springer-Link, and Cochrane Central Register of Controlled Trials) was performed. Six patients were treated conservatively with thyroxine with good results. The important question is: what is the driving force and the mechanism of transition(s) between these two types of many-body systems - with and without intrinsic decoherence?. Most DNA breaks accumulate in cultures trypsinized and seeded in medium supplemented with insulin, and irradiated in early G1. Once again, this exchange can only take place at early stages of the synthesis when the reaction is faster. To explore determinants of support for and reported compliance with smoke-free policies in restaurants and bars across the four countries of the International Tobacco Control (ITC) Four Country Survey.

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The presence of the proviral sequences in cells of the spleen and bone marrow of engrafted recipients was associated with significantly increased survival of mice treated with otherwise imovane dosage 15 mg lethal doses of MTX. Although signals of bikunin mRNA were faint in the whole brain of rats and mice, distinct signals were found in limited portions of rat brain, such as the hippocampus, cerebral cortex and pituitary, but undetectable in cerebellum, medulla oblongata, hypothalamus, striatum, midbrain and choroid plexus. It was found that after cimetidine therapy for 1 year: (i) the ultrastructural appearance of the parietal cells was normal, and (ii) the parietal cells responded normally to stimulation by pentagastrin. Thus flexion traction, rehabilitation positions, exercises, spinal manipulation, and surgical fusions in any position other than lordosis for the cervical and lumbar spines should be questioned. An unusual association of cleft lip/palate and upper extremity anomalies. The latter typically rely on simulations or on union-bound correction for assigning statistical significance to the results. This study was conducted in Sivas, a city located in the central Anatolia, between July 1 and August 31, 2007. Application of the cathode ray oscillograph to measurements of short life-periods of radioactive sources.

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Method for improved multiband excitation profiles using the Shinnar-Le Roux transform. Subclinical SARS-CoV infection was rare in a residential care home for the elderly with an outbreak of SARS. In doubtful cases, the clinical evolution and the demonstration of a monoclonal lymphoid B- or T-cell population may lead to a definite diagnosis. Synthesis and in vitro biocompatibility of injectable polyurethane foam scaffolds. The result indicates that the extra-long back fascia flap pedicled with descending branch of transverse cervical artery could be formed long enough to reach the opposite side of the neck and safely transferred to neck in one stage. Clinical outcomes of thoracic radiotherapy for locally advanced NSCLC with EGFR mutations or EML4-ALK rearrangement. On broiler meat, the maximum reduction achieved was 0.7 log and on broiler skin 0.8 log. We report here that neonatal PCB or low-level DES exposure resulted in the down-regulation of Wnt7a expression. The ras-like yeast YPT1 gene is itself essential for growth, sporulation, and starvation response. Three single-word repetition priming tasks were administered that varied in the degree to which visual-perceptual or conceptual processing was invoked.

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The negative results of this study, coupled with the observation of aggressive biological behavior of BCCs in previously irradiated patients merit further attention. Although CA125 antigen was adsorbed by 130-22 antibody, 125I-labeled 130-22 did not compete with OC125, indicating that although these two antibodies recognized CA125 antigen, they reacted with separate antigenic determinants. The knowledge of the formerly almost unexplored neurological manifestations of the periodic disease will contribute to improvement of the therapy of this rare ailment. They designed an artificial dermis consisting of bovine collagen and chondroitin-6-sulfate. Invasive pulmonary aspergillosis (IPA) remains a life-threatening infection in patients with prolonged neutropenia. Epidemiological studies identify malignancy as an independent VTE risk factor and show that cancer patients are at increased risk of both initial and recurrent VTE events. We have concluded that clinical endpoints used in clinical trials of ALS have frequently been insufficiently sensitive, non-linear, or even not intuitively highly relevant to the disease. Bovine mitochondrial ribosomes: effect of cations and heterologous dissociation factors on subunit interactions. The microvasculature and microcirculation of the cerebral cortex after arterial occlusion. The lack of Valpha3.2/Vbeta16 pairing was confirmed by TCR transfections.

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None of the mutant proteins with alterations at aa residue 102 possessed RNase activity. Multi-level factors associated with pregnancy among urban adolescent women seeking psychological services. A big helicopter or a special bus guided by a police car should be considered for hospital staff transport.(ABSTRACT TRUNCATED AT 250 WORDS). The severity of the sprains results from the possibility of either vertebral instability or objective neurovascular complications. influenzae biogroup aegyptius isolates from patients with noninvasive conjunctivitis. Experimental study of absorption, distribution, metabolism and excretion of salicylic acid and salicylate upon ageing showed that the sodium salicylate absorption rate is considerably decreased in old rats and rabbits.

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Tachycardia-induced right ventricular cardiomyopathy: epicardial radiofrequency ablation of an unusual and unexpected ventricular tachycardia. Manipulation of T-cell content in transplanted human bone marrow: effect on GVH and GVL reactions. The focus is on evaluating the needs of relatives of forensic patients, in particular, the problems resulting from the offence and a diagnosis of schizophrenia. The relation between the frequency of alternating current and the convulsive threshold of the albino rat. Contrast resolution was improved by the new technique, offering a wider latitude and edge enhancement. Previous angiographic studies have shown that coronary spasm occurs in association with the variant angina described by Prinzmetal, confirming his original hypothesis. It also handles the contribution of these sources of variance to the (co)variation of multiple phenotypes. The synthesis of sequence 71-86 of human proinsulin (sequence 6-21 of human insulin A-chain) via its monomeric cyclic dicystine peptide derivative (XXII) and the corresponding tetra-S-trityl-peptide derivative (XVIII) is described. The genetic basis of triple A (Allgrove) syndrome in a Greek family.

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