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Altezym

Altezym is a macrolide antibiotic used for various bacterial infections such as infections of the middle ear, throat, bronchus, sinuses, skin and soft tissue. It prevents bacterial growth. Azalides are a class of macrolide antibiotics which contain a nitrogen in the macrolide ring. This imparts different pharmacokinetic properties and is associated with greater stability of the molecule. One such Azalide is the antibiotic Altezym. It is also useful in treating pneumonia, typhoid, gonorrhoea, granuloma inguinale and chancroid.

Other names for this medication:
Arzomicin, Atizor, Azicid, Azigram, Azimax, Aziphar, Azithrus, Azitrim, Azitro, Azitrolit, Aziwok, Azomax, Azrolid, Bactexina, Fabramicina, Goldamycin, Gramokil, Iramicina, Macrozit, Neofarmiz, Nifostin, Novatrex, Novozithron, Odazyth, Ordipha, Phagocin, Ribotrex, Talcilina, Tanezox, Thiza, Tritab, Tromix, Trozocina, Vinzam, Zentavion, Zicho, Zimax, Zinfect, Zistic, Zithrox, Zitrex, Zitroken, Zitrotek, Zocin

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Also known as: Azithromycin

Description

Altezym (Altezym tablets and Altezym for oral suspension) contain the active ingredient azithromycin, a macrolide antibacterial drug, for oral administration. Altezym has the chemical name (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl) oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one. Altezym is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring. Its molecular formula is C38H72N2O12, and its molecular weight is 749.00.

Altezym, as the dihydrate, is a white crystalline powder with a molecular formula of C38H72N2O12∙2H2O and a molecular weight of 785.0.

Altezym is supplied as tablets containing azithromycin dihydrate equivalent to either 250 mg or 500 mg azithromycin and the following inactive ingredients: dibasic calcium phosphate anhydrous, pregelatinized starch, sodium croscarmellose, magnesium stearate, sodium lauryl sulfate, hypromellose, lactose, titanium dioxide, triacetin, and D&C Red #30 aluminum lake.

Altezym for oral suspension is supplied in bottles containing azithromycin dihydrate powder equivalent to 300 mg, 600 mg, 900 mg, or 1200 mg azithromycin per bottle and the following inactive ingredients: sucrose; sodium phosphate, tribasic, anhydrous; hydroxypropyl cellulose; xanthan gum; FD&C Red #40; and spray dried artificial cherry, creme de vanilla, and banana flavors. After constitution, each 5 mL of suspension contains 100 mg or 200 mg of azithromycin.

Dosage

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Altezym IV oral is taken by mouth. This medicine injection is given as an infusion into a vein, usually for 2 days before you switch to this medicine oral. A healthcare provider will give you this injection.

You may take Altezym IV oral with or without food.

Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Use Altezym IV for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Altezym IV will not treat a viral infection such as the flu or a common cold.

Store at room temperature away from moisture and heat. Throw away any unused liquid medicine after 10 days.

Detailed Altezym dosage information

Overdose

If you overdose Generic Altezym and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Altezym overdosage: discomfort feeling in stomach, diarrhea, retching, nausea.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not refrigerate or freeze the Zmax® extended-release oral suspension. After water has been added to the powder, use the dose within 12 hours and throw away any unused liquid after your dose.

You may store the Altezym® oral liquid at room temperature or in the refrigerator. Do not freeze the bottle. Do not keep the oral liquid for more than 10 days. Throw away any unused liquid after all doses are completed.

Detailed Altezym dosage information

Side effects

The most common side effects associated with Altezym are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use this medication if you have ever had jaundice or liver problems caused by taking azithromycin. You should not use azithromycin if you are allergic to it or to similar drugs such as erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), clarithromycin (Biaxin), telithromycin (Ketek), or troleandomycin (Tao).

There are many other medicines that can interact with azithromycin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

Take this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Azithromycin will not treat a viral infection such as the common cold or flu.

Avoid taking an antacid within 2 hours before or after you take azithromycin. Some antacids can make it harder for your body to absorb azithromycin.

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Rather than a single out-of-Africa dispersal scenario, we suggest that early modern humans were already divided into different populations in Pleistocene Africa, after which there followed a complex migration pattern. Hypoxic Proliferation of Osteosarcoma Cells Depends on Arginase II. Are estrogen receptor content in breast cancer and effects of tamoxifen on sex hormone-binding globulin markers for individual estrogen sensitivity?. Ratio-based lengths of intervals are, therefore, proposed to improve fuzzy time series forecasting. 11 cases were in stage III/B (on the basis of T4), and 10 were in stage IV (on the basis of M1). Intrasubject reproducibility of functional MR imaging activation in language tasks. The implementation of a new coagulation management method featuring the addition of the fibrinogen functional thromboelastography test to the TEG test according to an algorithm which provides for the administration of fibrinogen has helped in reducing the need for transfusion in patients undergoing liver transplantation with no impact on their survival. This paper reports a Chinese pedigree of CARASIL in which two patients exhibited all of the typical clinical features of the disease. The number of cycling HSCs increased after transplantation and remained elevated for at least 4 mo, while the frequency of HSCs in the bone marrow was completely regenerated by 2 mo after transplantation.

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Key to the success of the approach has been the emphasis on wide participation from all can biaxin treat bladder infection stakeholders. In this chapter, we describe methods for the purification of both untagged and polyhistidine-tagged tau protein. To study the repairing process and the factors causing subsequent surgery after trancervical resection of endomitrium (TCRE). However, when Tg B lymphocytes were compared with controls in B cell proliferation and IgE synthesis assays, the two were indistinguishable. To model sleep propensity (SP) as a continuous variable across 24 hours and to model the post-noon nap zone, or post-lunch dip in performance, and the early evening trough in SP. Trace metals in sediment cores from Deception and Penguin Islands (South Shetland Islands, Antarctica). We tested 18 candidate genes, by reciprocal hemizygosity, for their contribution to the observed phenotypic variation, and validated five genes and the chromosome II right subtelomeric region.

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