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Alpanol (Alprazolam)

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Alpanol is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alpanol, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alpanol is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Aaram, Alpose, Alpram, Alpranex, Alprasan, Alprocalm, Alpron, Alprowon, Alprozam, Alzorix, Ansilumirm, Belfa, Benzolam, Dipra, Dizeral, Endolam, Flunix, Imprax, Mediprex, Prazolam, Propnix, Prozam, Rivcam, Selamb, Somaspas, Somnarest, Trapose, Wycalm, Xanti, Xycalm, Zolran, Zopam, Zopic, Zopral

Similar Products:
Diovan, Anafranil, Glyburide, Cipro, Aldara, Tenormin, Momoz, Angizaar, Enacecor, Parlutal, Metolex, Asthamol, Zinfect,

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Take Alpanol XR exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Alpanol XR may be habit-forming and should be used only by the person it was prescribed for. Alpanol XR should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Do not crush, chew, or break a Alpanol extended-release tablet. Swallow the tablet whole. It is specially made to release alprazolam slowly in the body. Breaking the tablet would cause too much alprazolam to be released at one time.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

Your symptoms may return when you stop using Alpanol XR after using it over a long period of time. You may also have seizures or withdrawal symptoms when you stop using Alpanol XR.

Withdrawal symptoms may include blurred vision, trouble concentrating, loss of appetite, diarrhea, muscle twitching, numbness or tingling, or increased sensations.

Do not stop using Alpanol XR suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

To be sure this medication is helping your condition, your doctor will need to check your progress on a regular basis. Do not miss any scheduled visits to your doctor.

Store Alpanol XR at room temperature away from moisture, heat, and light. Remove any cotton from the bottle of disintegrating tablets, and keep the bottle tightly closed.

Keep track of how many pills have been used from each new bottle of this medicine. Benzodiazepines are drugs of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

Detailed Alpanol XR dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alpanol dosage information

Side effects

The most common side effects associated with Alpanol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Barium has superior physical properties of mucosal coating and radiographic density. Overall, none of the biomarkers displayed enough accuracy to be used clinically outside a research setting. Subsequently, in each region, the rate of apoptosis decreased with increasing age. The characterisation of supported platinum nanoparticles on carbon used for enantioselective hydrogenation: a combined electrochemical-STM approach. We ascribe this tendency to the enhanced optical absorption and the photo-induced thermal heating effect, which can be associated with the defect structure within the bandgap of Fe- TiO2 nanoparticles. Various semiquantitative PET parameters, pathological size of the hepatic lesion and clinical variables were correlated with survival outcome. Spinal tap revealed crystal clear fluid under an initial pressure equivalent to 120 mm of water with a protein content of 20 mg/dl. Evaluation of the diagnostic value of 64 simultaneously measured autoantibodies for early detection of gastric cancer. This paper describes the development of a computer-assisted self-directed learning module to teach carpal bone radiograph interpretation to clinical clerks, and the evaluation of its efficacy as a teaching tool. Effective dietary counselling in a dental setting can significantly reduce the risk of oral disease.

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Effect of intravenous glucose infusion on renal function in normal man and in insulin-dependent diabetics. One hundred forty-four Asian subjects with Fitzpatrick skin types III to V were treated with a cooled 40-ms alexandrite laser with fluences of 16 to 24 J/cm2. However, the role of anabolic (de novo amino acid synthesis) versus catabolic (proteolytic) processes in contributing to free amino acid pools is less understood. The postoperative course was uneventfull and there was progressive improvement of the sensory, motor and gait disturbance. Clinical significance of chloride intracellular channel 1 (CLIC1) in pancreatic ductal adenocarcinomas (PDAC) remains largely unknown. At the same time, inhibition of AQP1 decreased the pathological damage resulting from pulmonary edema. BeAM value: an indicator of the need to initiate and intensify prandial therapy in patients with type 2 diabetes mellitus receiving basal insulin.

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Characterization of oil sands acids in plant tissue using Orbitrap ultra-high resolution mass spectrometry with electrospray ionization. Multiplexed next-generation sequencing and de novo assembly to obtain near full-length HIV-1 genome from plasma virus. Women with preexisting conditions might be advised to delay sterilization until the hypercoaguability of pregnancy has resolved. ICS clearly improve asthma control in children with mild to moderate persistent asthma, but it is not clear that they can alter the natu-ral history and progression of asthma. Rare-earth glass reference materials for near-infrared spectrometry: correcting and exploiting temperature dependencies. Logistic regression was used to identify univariate and multivariate odds ratios (OR) for correlation of age and risk factors. Findings, such as the association of trans fat with cardiovascular disease, have helped shaped medical guidelines and government policies. Temporal T807 binding correlates with CSF tau and phospho-tau in normal elderly. Identifying these modifications via standard database searching can incur significant performance penalties.

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Simultaneous isolation of Nocardia asteroides and Corynebacterium pyogenes hominis from mycetoma. We tested whether a true causal relationship exists between edema and cardiac dysfunction. Because of reports of bromide intoxication in rural areas, we speculate that some of these cases may be secondary to contaminated water supplies. This retrospective cohort study included all pregnant women with red blood cell (RBC) antibodies who were tested between 1993 and 2008. Regulation of the inflammatory processes by maggots contributes to their beneficial effects on chronic wounds.

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Unsupervised procedures by surgical trainees: a windfall for private insurance at the expense of graduate medical education. Tehcnetium bone scanning is a diagnostic technique for determining bone infection in children who are unable to communicate adequately or in those whose signs have been modified by previous inadequate antibacterial therapy. Knockdown of GGPPS expression with small-interfering RNA abolished the EGR-1-activated Erk1/2 activity. c-kit protein expression was detected in 52 formalin-fixed and paraffin-embedded SCLC, 20 non-small cell lung cancer (NSCLC) and 10 normal lung tissues by immunohistochemistry with rabbit antibody to human c-kit protein. Flocculation is one of the most widely applied techniques for water treatment and sludge dewatering.

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Acute care congress on the future of emergency surgical care in the United States. In vitro/in vivo phototoxic risk assessments of griseofulvin based on photobiochemical and pharmacokinetic behaviors. Density functional theory calculation was conducted in an attempt to understand the mechanism and the origin of the regioselectivity. In nature, the main microbes of lignocelluloses deconstruction are fungi. Concomitantly, ezrin may act simultaneously as a regulatory or deregulatory chaperon in both normal and tumor cells.

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Various aspects of Candida albicans infection and its treatment with nystatin. The results show that, as predicted by the homoiology hypothesis, regions of the human cranium related to mastication were more variable than non-masticatory regions. The chondrogenic differentiation potential of the easily accessible adipose tissue-derived stem cells (ASCs) is of particular interest within the field of tissue engineering for treating cartilage defects. New heterometallic carboxylate frameworks: synthesis, structure, robustness, flexibility, and porosity. To evaluate whether clinical varicoceles are associated with abnormal semen parameters and whether varicocelectomy could improve the parameters in patients with causes other than infertility. The assessment of thyroid function in children with short stature provides the evidence that measurement of IGF-I concentration may be a procedure reliable at least to the some degree in diagnosing GHD as the results of GHST. Coronary computed tomographic angiography using low-dose prospectively electrocardiographic triggered high-pitch spiral acquisition by dual-source computed tomography: image quality and radiation dose. One hundred eighty-seven ranibizumab-treated patients diagnosed as having subfoveal CNV scarring in the untreated eye were compared with a control group of untreated unilateral subfoveal CNV scarring.

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Symposium on atherosclerosis and metabolism of the arterial wall. The relationship between physique and rate of skeletal maturation in boys. Patients with GP experience other associated conditions, including gastroesophageal reflux disease, gastric bezoars and small bowel bacterial overgrowth. The role of clinical simulations as a teaching and evaluation device for preclinical medical students. The evaluation of the rates of biological processes from tracer kinetic data. Further studies confirming the presence of a quantitative trait locus in this region and evaluating these candidate genes may help explain the association of elevated sodium-lithium countertransport and hypertension. However, upon exposure to TEA, the duration of spontaneous action potentials is prolonged. Comparative analysis of TACE alone or plus RFA in the treatment of 167 cases of intermediate and advanced staged primary hepatocellular carcinoma.

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This study aimed to clarify the prevalence of anger and impulsivity and its associated factors through a nationwide survey of junior and senior high school adolescent students in Japan. A substrate-specific cytochrome P450 monooxygenase, CYP6AB11, from the polyphagous navel orangeworm (Amyelois transitella). Carotid plaque with hemorrhage leads to cerebral embolism and ischemic stroke. Service engineering for grid services in medicine and life science. Mycaperoxide H, a new cytotoxic norsesterterpene peroxide from a Thai marine sponge Mycale sp.

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Hypoglycemia as a complication of the use of GIK solution in patients with hepatic dysfunction, malnutrition and low cardiac output is discussed. The isolated chromatins were studied by circular dichroism and for their ability to bind the intercalating dye, ethidium bromide. Preparation for repeated study of left ventricular function in the conscious dog. A nonrandomized, within-subject design was implemented to investigate vowel and consonant recognition and fricative articulation of school-age children utilizing this feature. Cholera control in an inaccessible district in Tanzania: importance of temporary rural centres. Arsenic exposure may be responsible for elevated rates of bladder cancer in three states. In this report it is suggested that the specific adrogen-binding protein (ABP), previously shown to originate in the testis of rat and other species, is produced by the Sertoli cells. Social adversity is a risk factor for psychosis, but the translating mechanisms are not well understood.

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In Their Own Voices: Breaking the Vicious Cycle of Addiction, Treatment and Criminal Justice Among People who Inject Drugs in Ukraine. We present a rare case of malignant rhabdoid tumor (ovarian small cell carcinoma of hypercalcemic type) in a 24-year-old female with fulminant course. Every expert must know what type of disease corresponds to the knowledge acquired during the studies in the University School as well as to the functions permitted by the authorities, always thinking to get the best results to the patients, the families and the surrounding people. Posteriorly nifedipine safety in breastfeeding , it fuses with a second septum, which is of purely ventricular origin. Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for the treatment of rheumatoid arthritis not previously treated with disease-modifying antirheumatic drugs and after the failure of conventional disease-modifying antirheumatic drugs only: systematic review and economic evaluation. To compare the efficacy of two regimens of low dose human chorionic gonadotropin (hCG) on follicular response and oocyte maturation in women with polycystic ovarian syndrome (PCOS). It is important to continue treatment with the optimal combination of these drugs and prolong progression-free survival (PFS) to improve overall survival (OS). Changes in family relationships affect the development of chemotherapy-related nausea symptoms. This method involves using accelerated protons to excite inner-shell electronic transitions of target atoms and recording the resultant X-rays to characterize the trace element concentrations.

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Pulmonary 64-MDCT angiography with 50 mL of iodinated contrast material in an unselected patient population: a feasible protocol. To explore differences in gait endurance, speed, and standing balance in people with multiple sclerosis (MS) across the Disease Step Rating Scale, and to determine if differences are statistically significant and clinically meaningful. Statistics of Vaccination and of Small Pox in the City of Mexico from 1872 to 1895. The specificity of the three assays was validated following DNA sequencing of the samples genotyped. Metal complexes with two different hydrogen-bond donor ligands as anion hosts.

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Many adults with congenital heart disease encounter late complications. Internal mammary node (IMN) metastasis has a similar prognostic importance as axillary nodal involvement. The aim of this review was to evaluate the effects of Trizivir, a fixed-dose combination of three NRTIs (abacavir-lamivudine-zidovudine) for initial treatment of HIV infection. The histological distinction of chondroma versus chondrosarcoma is not essential for the clinical management of these lesions, and we suggest they be designated as cartilaginous tumors of the larynx. However, we have an incomplete understanding of the mechanism of ligand binding for these newly discovered hemoglobins and the measurement of their kinetic parameters depend on their coordination at the heme iron. Ligament insertion sites on the femur, patella, and fibula can be derived from computed axial tomography scans.

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Age of puberty has declined substantially in developed settings and is now declining in the rest of the world with economic development. Pre-metamorphic larvae and post-metamorphic adults require carrier-primed amplification in order to generate an anti-hapten response. The presence of the synthetic photosensitizers generally enhanced photoinactivation of Gram-positive facultative anaerobes (Ent. Simultaneous correction of aortic coarctation and rheumatic mitral stenosis in a 45-year-old patient. Neither association between p58PITSLRE or p110PITSLRE and PAK1 nor association between p110C and PAK2 or PAK3 was observed. FTY720 stimulates multidrug transporter- and cysteinyl leukotriene-dependent T cell chemotaxis to lymph nodes. The present study aims to assess the singing vocal health using Singing Voice Handicap Index-10 (SVHI-10) in these singers and to compare between those who report voice problem and those who do not. Mu and kappa, but not delta, agonists reduced the amplitude of evoked IPSCs and appeared to colocalize in a significant portion of GABAergic terminals onto POMC neurons. However, previous ED-based studies of urban children with asthma have reported low follow-up rates. We have identified possible cichlid lineage-specific changes, including losses of a subset of dlx expression domains in the pharyngeal teeth, which will be the targets of future functional studies.

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Post hoc analyses suggested that Reiki may have had limited effects on mood and energy amaryl 6 mg levels. In vivo aqueous humor oxygen tension--as estimated from measurements on bare stroma. Resveratrol and curcumin are plant-derived substances with biological properties that may have immunomodulatory properties. Electrochemical chip-based genomagnetic assay for detection of high-risk human papillomavirus DNA. Microsurgical lymphvessel-transplantation for the treatment of lymphedema: experimental and first clinical experiences.

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Measurement of brain tissue oxygen saturation in term infants using a new portable near-infrared spectroscopy device. When 14C-labeled cyclophosphamide and nitrogen mustard were incubated separately with normal lymphocytes and lymphocytes from patients with chronic lymphocytic leukemia, the amount of radioactivity associated with the normal cells far exceeded that detected on the leukemic lymphocytes. Also, the anticonvulsant activity of ondansetron in combination with phenytoin and its effect on the cognitive deficits induced by phenytoin were studied. Three cancer patients were treated with rt-PA and captopril, and their pretreatment and post-treatment plasmas were tested for antiangiogenic activity in vitro. A new method of investigating the perception of prosodic features. We conclude that interaction of the Yersinia type III translocator factor YopB with the host cell triggers a proinflammatory signalling response that is counteracted by multiple effectors in host cells. Noninvasive cardiac imaging modalities include chest radiography, single photon-emission CT myocardial perfusion imaging, echocardiography, multidetector CT, PET, and MRI.

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Discovery of a novel protein kinase B inhibitor by structure-based virtual screening. As a demonstration of efficient implementation, we showcase LFPs from mathematical models of electrotonically compact cerebellum granule neurons and morphologically complex neurons of the neocortical column. BxpB appears to be glycosylated or associated with glycosylated material and is encoded by a gene that (along with bclA) may be part of an exosporium genomic island. Assignment of retinal dystrophy (rdy) to linkage group IV of the rat. The physician and teacher as team: assessing the effects of medication. The mRNA quantities of H2afz, Actb, Bax, Bad and Bcl2 were reduced at a similar rate, but the decreases in Bcl2l2 and Trp53 mRNA were significantly greater. We searched for hypertrophic chondrocytes by assessing RUNX-2, type X collagen, and matrix metalloproteinase 13 (MMP-13) expression, for osteoblasts by analyzing RUNX-2, CD56, and type I collagen expression, as well as for signs of new bone formation. Near infra-red (NIR) spectroscopy was applied to investigate freeze-dried samples containing varying ratios of the commonly used excipients mannitol and sucrose.

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Allogeneic ADM combined with STSG transplantation prevents scar contracture and has obvious effect in improving function and appearance. The aim of this study was to assess the success rate of conservative medical treatment with methotrexate (MTX) in the dose of 1 mg/kg intramuscularly in patients with ectopic pregnancy or persistent pregnancy of unknown location and to compare the results of clinical history, clinical finding and laboratory results in a group of successful and a group of unsuccessful treatment. Clearfil Esthetic in A3, A4, and Z3 performed better than RelyX ARC. Another notable common property between some populations was the high umbelliprenin content in aerial plant parts. Establishment of a cell line panel as an alternative source of platelet antigens for a screening assay of anti-human platelet antibodies.

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The progressive stages in Bdellovibrio bacteriovorus penetration into two strains of Escherichia coli were examined by use of electron microscopic techniques. Patients with LVD were older and had a high incidence of diabetes mellitus, atrial fibrillation, coronary artery disease, and severe stroke symptoms. MHC class II expression by beta2 integrin (CD18)-positive microglia, macrophages and macrophage-like cells in rabbit retina. Biomolecules have been attached to porous silicon amaryl maximum daily dose by a new linking method that forms a direct Si-C bond on the surface and retains the photoluminescence of the porous silicon. Immunopathology of the kidney in disseminated lupus erythematosus.

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