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Alfix (Alprazolam)

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Alfix is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alfix, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alfix is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Actirax, Alfix, Alfresh, Alparazole, Alpose, Alpramax, Alpranex, Alpron, Alprotame, Alrif, Altin, Alzom, Alzonex, Alzorix, Alzoset, Ambusyn, Copax, Dazolam, Ecsit, Endep, Exiten, Fledore, Fluxin, Indolam, Pacyl, Propnix, Prosanti, Rivcam, Samprex, Somnarest, Stresnil, Tagat, Trazopin, Visram, Zedel, Zenax, Zolam, Zolran, Zoltweet, Zolyde, Zotin

Similar Products:
Rebetol, Ativan, Theolair, Nexium, Caverta, Sumycin, Ventiphylline, Santibi, Avistar, Fertex, Hormorin, Aptogrel, Viscab, Clonocid, Epinor, Ranitol,

Also known as: Alprazolam


Alfix XR (alprazolam) is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Alprazolam affects chemicals in the brain that may become unbalanced and cause anxiety.

Alfix XR is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

Alfix XR may also be used for other purposes not listed in this medication guide.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alfix. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


If you have been prescribed Alfix for medical reasons, the best way to avoid a Alfix overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alfix consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alfix are:

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The significance of these findings for the understanding of chemotherapy-induced nausea in the clinical population is discussed. In this prospective, open, randomized study comparing early CNI withdrawal with mammalian target of rapamycin inhibitors immunosuppression during the first year after HTx, early transition from CNI-based immunosuppression to EVR-based treatment did not result in differences in microvascular function as assessed by the IMR. Several other fibrous sheath proteins have been identified, but how the fibrous sheath assembles is not understood. The resistance of pathogenic bacteria to existing antibiotics has become a global epidemic. Prolactin and growth hormone secretion in chemically induced and genetically obese mice. The plasma total antioxidant status (TAS), total oxidant status (TOS), and oxidative stress index (OSI) were determined.

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Target-specific modulation of the descending prefrontal cortex inputs to the dorsal raphe nucleus by cannabinoids. In this paper, we examine recent data which suggest that the observation of non-targeted responses may not be universally observable for differing radiation qualities. All had oral abnormalities affecting the palate, teeth, and/or lips, including wide spacing between the teeth, screwdriver-shaped upper incisors, hypodontia, delayed tooth eruption, narrow spacing in the upper canine area, large pulp chambers of the upper incisors and permanent molars, external root resorption of the upper central incisors and permanent molars, a division of the lower third of the root canal in normally one-rooted teeth, tooth retention, retrognathia of the upper jaw, a high palate or cleft lip/palate, and microforms of lower lip fistula. Experimental analysis of the mechanisms of somite morphogenesis. The dynamic index was small and increased in direct proportion to the rate of stretch. Low-energy X-radiation for prevention of restenosis results in localized inhibition of V79 fibroblast cell proliferation. The present study thus reveals the presence of functional cis-regulatory elements in the promoter region of the murine Npr1 gene and its transcriptional downregulation by vasoactive peptide Ang II.

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Resection or degeneration of uncovertebral joints altered the segmental kinematics and load-sharing pattern of subaxial cervical spine: A biomechanical investigation using a C2-T1 finite element model. Host associations of permanent ectoparasitic mite Marsupialges misonnei Fain, 1963 (Acariformes: Psoroptidae: Marsupialginae) are analyzed. If proven effective, this universal social connectedness program for suicide could be more widely delivered in Australian high schools, providing a valuable new resource. All indices improved after surgery, but only distortions and macular volume normalized. Patterns of recurrence in patients with melanoma and histologically negative but RT-PCR-positive sentinel lymph nodes.

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Here we describe a pooled GWAS study undertaken to find novel genes associated with human episodic memory performance. Temperature Values Variability in Piezoelectric Implant Site Preparation: Differences between Cortical and Corticocancellous Bovine Bone. Both blastocyst homogenates and extracts of blastocyst homogenates were luteotropic. To examine the relationship between three-dimensional mandibular morphology and growth hormone receptor (GHR) gene variants in a healthy Japanese population. Immunohistochemical localization of cocaine- and amphetamine-regulated transcript peptide (CARTp) in the brain of the pigeon (Columba livia) and zebra finch (Taeniopygia guttata). SHR may have further genomic actions, that do not involve direct DNA binding, through protein-protein interactions with other sequence specific transcription factors, although these may still involve weak binding to nonconsensus steroid responsive elements in vivo. Multiloop edgewise archwire (MEAW) mechanics were used and resulted in an efficient bite closure and good occlusion. In normal persons (males and females) in mature age (30-45 years) a decrease of the enzyme activity takes place which is connected with an increase of the triglyceride content.

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A preliminary report on a Brucella isolated from the desert wood rat, Neotoma lepida Thomas. The latent neural pathway is not latent in neonatal rats as shown by the spontaneous expression of crossed phrenic activity. Advantages of genetic testing commonly identified included benefit to themselves and family members through the possibility of earlier diagnosis and targeted therapies. Radiographic appearance and clinical progress after excision arthroplasty of the canine hip. In long-term haemolysis the iron deficiency increases, in most cases the haemolysis a little decreases, and a deficiency of erythropoietin is not to be established. Letter: Seize of hospital, fulfillment of educational commission and dermatological care for the population. To assess the comparative effect of gabapentin versus gabapentin plus celecoxib on pain and associated complications after laminectomy.

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Can thiol compounds be used as biomarkers of aquatic ecosystem contamination by cadmium?. The research covered 30 female patients and the results pointed to great usefulness of this method in diagnostics of malignant breast tumour. Multifocal iris melanoma treated with total anterior segment palladium-103 plaque radiation therapy. The stationary phase of superheated water chromatography must be stable against the attack of water. A recent investigation of families containing two and three consecutive generations affected with Type I (insulin dependent) diabetes mellitus has led to speculation that there is a second susceptibility gene, not linked to the major histocompatibility complex. Target size matters: target errors contribute to the generalization of implicit visuomotor learning. This trial was registered at as NCT00011713. Problematic Internet Use During Adolescence and Young Adulthood.

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