An approach to the problem of heterogeneity of human tumour-cell populations. Despite breast health promotion campaigns, many women delay for one month or more, in seeking help from a health care professional for self discovered breast symptoms. Eye Department, Bnai-Zion Medical Center, and the Faculty of Medicine, the Technion, Haifa, Israel. Emeritus Chief, Laboratory of Pathology, National Cancer Institute. Many academic surgeons reported that their educational debt affected their academic productivity, career choices, and quality of life. Identification and characterization of class 1 integrons in bacteria from an aquatic environment. Interestingly, overexpression of the 3 Id genes in bone marrow-derived monocyte/macrophage lineage cells (BMMs) inhibits the formation of tartrate-resistant acid phosphatase (TRAP)-positive multinuclear osteoclasts, but it does not alter the ability of BMMs to either phagocytose or differentiate into dendritic cells (DCs).
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These growth factors bind cognate receptors on surface of target cells, and stimulate specific intracellular signals. Rats maintained on a protein-free diet for 3 days have an altered time course of hepatic DNA synthesis during liver regeneration. It has not been decided to what extent the results from statin trials should be transferred to clinical practice in the very old. Not all of these agents will eventually be marketed but they will all help us gain insight into the pathophysiology of multiple sclerosis and decipher the mechanisms that underlie its heterogeneity. It was concluded that formaldehyde concentration did not increase with time. The results of experiences from a number of clinical centers are available. Influence of hypophyseal hormone and of nervous impulses on the colour-dress of hermaphrodite teleostean fish. Differential involvement of PKA and PKC in regulation of catecholamine enzyme genes by PACAP.
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The purpose of this study was to evaluate adaptation to the electropalatograph (EPG) from the perspective of consonant acoustics, listener perceptions, and speaker ratings. CPT-11 is a useful treatment for multiple drug resistant recurrent breast cancer. We tested the hypothesis that a decline in lung function within the normal range may be associated with a systemic subclinical inflammation. Dental students have to face the additional stress of their studies in addition to the stresses related to dentistry as a profession. Microneurovascular free muscle transplantation for reanimation of facial paralysis. Temporal variability and effect of environmental variables on airborne bacterial communities in an urban area of Northern Italy.
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When photostimulated (20:4-h light-dark), birds increased daily caloric intake and gained weight rapidly. Although LPA and S1P activated both PI3K/Akt and Ras/ERK signaling through G(i), anastellin inhibited only the Ras/ERK pathway. Several clinical trials examining the effects of peppermint oil on irritable bowel syndrome (IBS) symptoms have been conducted. Differences in the effects of amphetamine and methylphenidate on brain dopamine turnover and serum prolactin concentration in reserpine-treated rats. Mucins are the predominant glycoproteins found in gastrointestinal epithelia, and their structures differ according to the location in the GI tract and the state of cellular differentiation. Anesthetized tissue inhibitor of matrix metalloproteinase-3-deficient mice were subjected to coronary ligation followed by intramyocardial injection of vector-transfected bone marrow stromal cells, bone marrow stromal cells overexpressing tissue inhibitor of matrix metalloproteinase-3, or medium. Guazuma ulmifolia extract (GUE) completely inhibited cholera toxin-induced secretion if the extract was added to the mucosal bath prior to the toxin. TVC contained higher levels of HDEL-bearing proteins than ordinary ER cisternae.
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Assessment of natural background can practically be made by two means. Milk secretory immunoglobulin A was analyzed by enzyme-linked immunosorbent assay. Pleurodesis was assessed at 28 days according to a 1-8 point scoring system and pleural fibrosis and inflammation assessed histologically on a 0-4 point scale. Safety assessment of stearyl heptanoate and related stearyl alkanoates as used in cosmetics. We have reported that the production of IL-5 and IL-13 by mite-responsive T helper cells (Th) is controlled under similar signal requirements, but precise mechanisms are not yet well characterized. A synthetic 48 bp operator fragment was used to determine the repressor-operator dissociation constant in the presence of tryptophan or tryptophan analogs which have higher or lower affinities for aporepressor.
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The fraction IV significantly reduce death rate of mice infected with HSV- I. Since computed 3D structures of millions of compounds are available, the knowledge of their binding conformations would be a great benefit for the development of efficient screening methods. Mouse complementary DNA microarrays were used to screen for differences in expression during pregnancy in C57BL/6 mice. The combination of LTD(4) and TXA(2) receptor antagonists exhibited significant effects irrespective of the condition used. Decrease of testosterone, cholesterol and ascorbic acid in the rat testis after administration of pineal polypeptides. Deoxyribonuclease II (DNase II) activity in mouse tissues and body fluids. Especially for patients performing regular physical activity who suffer from mild hypertension, calcium antagonists provide a viable therapeutic alternative to beta-blockers. The digester fed with the thermally pretreated manure had a higher methane productivity and an improved removal of the volatile solids (VS).
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Syndromes constitute a core aspect in the study of Chinese medicine, and research on the concept of syndromes is important to the study of the process of modernization of traditional Chinese medicine. Not surprisingly, work settings like hospitals rely more intensively on clinical guidelines than the other work settings (health ministries or agencies and regional health authorities). The use of ultrasound for measuring ovarian volume has attracted increasing interest in recent years, as it appears to be a valuable technique for identifying tumors in certain risk groups for ovarian carcinoma. The enzyme responsible for iodide salvage in the thyroid, iodotyrosine deiodinase, was solubilized from porcine thyroid microsomes by limited proteolysis with trypsin. We performed subtractive and differential hybridization for transcript comparison between murine fibroblasts and isogenic epithelium, and observed only a few novel intracellular genes which were relatively specific for fibroblasts. The study and its presentation in this context would be helpful for novice researchers in the area of medical expert system. The process by which the AUA codon is translated as Met in the mitochondrial system remains to be clarified.
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Inflatable trays for the prevention of contamination in surgery. Recent progress in understanding the pathophysiology of hypoxic-ischemic encephalopathies and intraventricular hemorrhages have enabled us to propose new therapeutic modalities in preventing the development and severity of these disorders in the newborn. Estimated radiation dose associated with cardiac CT angiography. Current strategies for the treatment of osteoporosis rely almost exclusively on agents whose pharmacological actions are primarily antiresorptive. Furthermore we check whether structural changes occur upon application of strong electric fields.
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Treatment of the SCF-responsive human hematopoietic cell line MO7e with the inhibitor of Src family kinases PP1 blocked SCF-induced capping of c-Kit and internalization of c-Kit. A core element of this will be the specification of appropriate goals for commissioning. Classical CAH-CYP21 in females allows the study of the effects of hyperandrogenism and chronic glucocorticoid exposure. Nonetheless, relatively little is known about intestinal DC responsiveness to innate immune stimuli via TLRs. Psychophysiology of schizophrenic disorders of attention--concepts, findings and working hypotheses. We validated the classifiers with data from an independent cohort of 75 patients with stage IB NSCLC. In the latter half of life men tend to shift from active to passive mastery, women the opposite. Eighty-two SON neurons were antidromically identified and 63 of these increased their firing rates during complete occlusion of the right carotid artery. After stratification by epsilon4 allele status of the apolipoprotein E gene, TT-241-240P2 homozygosity of the SIGMAR1 gene reduced the risk of AD in epsilon4 allele carriers by three-fourths.
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high heels for females or electric shavers for males can modulate gender perception of a face. Biopsies from 34 cases with vulvar white lesion, including 12 cases with lichen sclerosus (LS), 18 with squamous hyperplasia (SH) and 4 SH accompanied with LS, were examined for protein expression of cyclin D1 and p16 using immunohistochemical techniques. The p53 inhibitor, pifithrin-alpha, is able to attenuate the effect of proteasome inhibition. Improved accessibility and reactivity of dissolving pulp for the viscose process: pretreatment with monocomponent endoglucanase. Based on a symmetry assumption, overall mean velocity for the total cross section was computed, and the magnitude of error in estimation of total flow from measurement of velocities at different depths was calculated. Prophylactic fluconazole is effective in preventing fungal colonization and fungal systemic infections in preterm neonates: a single-center, 6-year, retrospective cohort study. Liver cirrhosis is associated with increased prevalence of gastrointestinal symptoms, insulin resistance, and altered gut transit. Is there a synergy between physical exercise and drug therapies for osteoporosis?. Objective evaluation of vessel attenuation in multidetector-row computed tomographic pulmonary angiography using high-density contrast material for the detection of pulmonary embolism.
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Multivariate logistic regression analysis determined significant indicators of midface fracture. Operating room of a plastic surgery hospital of the Chinese Academy of Medical Sciences and the Peking Union Medical College. Persistence of respiratory symptoms in ex-underground iron ore miners. Digital image DNA cytometry: a useful tool for the evaluation of malignancy in biliary strictures. The technique is based on wavelet transform of the original image combined with vector quantization (VQ) of high-energy subbands using the LBG algorithm. Neuromuscular choristomas arising in connection with congenital lipomas may derive from a dysembryogenic process of stem cells of the caudal neural tube.