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Alenost (Alendronate)
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Alenost

Alenost is a bisphosphonate drug that prevents osteoclastic bone resorption which is used for the prevention and treatment of osteoporosis. Alenost is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease.

Other names for this medication:
Alant, Alendix, Alendronate, Alenost, Bifosa, Denfos, Osteofos, Ostogee, Poronil, Ralenost, Restofos, Zophost

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Periactin, Lexapro, Allegra, Levothroid, Sporanox, Celexa, Cenforce, Imovane, Singulair, Chloromycetin, Sigmaxin, Urifine, Pichromet, Cefid, Wellbutrin, Flusenil, Vermin, Domzole,

Also known as: Alendronate

Description

Alenost (alendronate) is a bisphosphonate (bis FOS fo nayt) medicine that alters bone formation and breakdown in the body. This can slow bone loss and may help prevent bone fractures.

Alenost is used in women to treat or prevent osteoporosis caused by menopause and in men and women to treat osteoporosis caused by taking steroids.

Alenost is also used to increase bone mass in men who have osteoporosis, and to treat Paget's disease of bone in men and women.

Dosage

Take Alenost exactly as prescribed by your doctor. Alenost is taken either once daily or once per week. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take Alenost first thing in the morning, at least 30 minutes before you eat or drink anything or take any other medicine. If you take this medicine only once per week, take it on the same day each week and always first thing in the morning.

Take with a full glass (6 to 8 ounces) of plain water. Do not use coffee, tea, soda, juice, or mineral water. Do not eat or drink anything other than plain water.

Do not crush, chew, or suck on an Alenost tablet. Swallow the tablet whole.

For at least 30 minutes after taking Alenost:

Do not lie down or recline. Do not take any other medicine including vitamins, calcium, or antacids.

Pay special attention to your dental hygiene while taking Alenost. Brush and floss your teeth regularly. If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using alendronate.

Alenost is only part of a complete program of treatment that may also include diet changes, exercise, bone mineral density testing, and taking calcium and vitamin supplements. Follow your doctor's instructions very closely.

Store at room temperature away from moisture and heat.

Your doctor will determine how long to treat you with this medicine. Alenost is often given for only 3 to 5 years.

Detailed Alenost dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Drink a full glass of milk and call your local poison control center or emergency room right away. Do not make yourself vomit and do not lie down.

Overdose symptoms may include muscle cramps, numbness or tingling, tight muscles in your face, seizure (convulsions), irritability, and unusual thoughts or behavior.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alenost are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take Alenost Plus D if you have low levels of calcium in your blood (hypocalcemia), or a problem with the movement of muscles in your esophagus.

Do not take a Alenost Plus D tablet if you cannot sit upright or stand for at least 30 minutes. Alendronate can cause serious problems in the stomach or esophagus (the tube that connects your mouth and stomach). You will need to stay upright for at least 30 minutes after taking Alenost Plus D.

To make sure Alenost Plus D is safe for you, tell your doctor if you have:

low blood calcium (hypocalcemia); a cancer such as sarcoidosis, leukemia, lymphoma; a vitamin D deficiency; kidney disease; or an ulcer in your stomach or esophagus.

In rare cases, this medicine may cause bone loss (osteonecrosis) in the jaw. Symptoms include jaw pain or numbness, red or swollen gums, loose teeth, or slow healing after dental work. The longer you use Alenost Plus D, the more likely you are to develop this condition.

Osteonecrosis of the jaw may be more likely if you have cancer or received chemotherapy, radiation, or steroids. Other risk factors include blood clotting disorders, anemia (low red blood cells), and a pre existing dental problem.

Talk with your doctor about the risks and benefits of using this medication.

It is not known whether Alenost Plus D will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether alendronate and cholecalciferol passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

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In situ hybridization study of PSP94 (prostatic secretory protein of 94 amino acids) expression in human prostates. Developing countries in Africa, Asia, and the Caribbean and Central/South America. Biochemical analysis of the adult female salivary glands revealed apyrase, alpha-glucosidase and lysozyme activities. A histochemical analysis of the development of the small intestine of human fetuses. In 6 tumors IL-10 mRNA was detectable at a higher titer in the progression zones. Accumulation of specific amino acid substitutions in HLA-B35-restricted human immunodeficiency virus type 1 cytotoxic T lymphocyte epitopes.

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Quantitative flow cytometric and clonogenic evaluation of glass bead affinity fractionation of antibody-labeled murine bone marrow. Murein synthesized in ether-permeabilized cells of Escherichia coli deficient in individual penicillin-binding proteins (PBPs) and in the presence of certain beta-lactam antibiotics was analyzed by high-pressure liquid chromatography separation of the muramidase split products. However, careful risk assessment should focus on reduction of injury to patients as much as to healthcare workers. Prevention and a high index of suspicion will decrease morbidity. They are released when bone is resorbed so that osteoclasts and their precursors may be exposed to high local concentrations. The stressed-out rat: a model for anesthetic prevention of post-traumatic stress disorder. Clinically, the differential diagnosis is breast carcinoma, Paget disease and galactophoric dilatation. Type IV collagen alpha chains of the basement membrane in the rat bronchioalveolar transitional segment.

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Ciliated biliary epithelial cells in the livers of non-human primates. MBD2 plasmid was constructed, and the lentivirus system expressing MBD2 was produced in 293FT cells. Analysis of products digested by glycosyl hydrolases helps understanding of the hydrolysis mechanism and the substrate recognition in the enzymes. Hence, this presents an effective pathway for the identification of the bacteria present in unknown samples of various origins. The use of multiscale analysis, through biorthogonal wavelets presented in this paper, appears very promising for such a characterization. To overcome these limitations we developed a novel B0 mapping method using multiple evolution times with a novel unwrapping scheme in combination with a user-defined ROI selection tool.

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Definition of cancer cachexia: effect of weight loss, reduced food intake, and systemic inflammation on functional status and prognosis. Cisplatin, adriamycin, etoposide, megestrol acetate versus melphalan, 5-fluorouracil, medroxyprogesterone acetate in the treatment of endometrial carcinoma. In addition, the peculiar immunophenotype of infiltrating cells (CD3, CD4, CD8, CD25) and their correlation with HLA-DR expression before and after treatment with oral cetirizine, a highly selective, third generation H1-receptor antagonist has been examined using the labeled avidin biotin (LAB) system. Amino acid content of the antigen of structure A in adenovirus 5. The aim of this case presentation is to emphasize the importance of dentists on diagnosis and prognosis of oral malignancies. Participants who received specialized benefits counseling achieved significantly greater improvements in earnings. Performance of the proposed algorithm is evaluated using both real and simulated ultrasonic data. Experience of telemedicine and information network system at Hokkaido University Hospital. Relation between the physician and pharmacist in the Canton of Berne: various historical aspects.

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Medical and surgical treatment of aphakic cystoid macular edema. Health Realization/Innate Health: can a quiet mind and a positive feeling state be accessible over the lifespan without stress-relief techniques?. BAd3 vector efficiently transduced the heart, kidney and lung in addition to the liver and spleen and persisted for a longer duration compared to PAd3 or HAd5 vectors. We also established the method for analyzing aggregate interacting proteins (AIPs) and reported several AIPs including transcription factor NF-Y. A second mechanism of plasmid-mediated resistance to gentamicin was detected in animal strains of E. Although it has been widely held that CRPS in children is intrinsically different from adults, there appear to be relatively few differences. AKE completely suppressed growth of the yeast form fungi, Saccharomyces cerevisiae A 5 8 1 A, Schizosaccharomyces pombe JY 1 and Candida albicans ATCC 36232 at a concentration of over 16 micrograms/mL. Future perspectives include longitudinal studies to further elucidate the association between medial olivocochlear bundle-activity and permanent threshold shift in humans.

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Studies using reflexology foot massage techniques as the intervention versus sham reflexology treatment, simple foot massage, conventional treatment, or no treatment as the control were then selected. Previously isolated human placental cDNA clones represent a fusion of specific RNA sequences encoded by two genes: lysosomal chitobiase (CTB) and G-protein gamma 5 subunit (GNG5, Fisher and Aronson, 1992a, 1992b). The RhlR-RhlI regulatory system was found to be essential for the production of elastase as well, and cross-communication between the RhlR-RhlI rhamnolipid regulatory system and the LasR-LasI elastase regulatory system was demonstrated. These compositional analyses focused on attributes believed to be important determinants of nutritional quality of marine vertebrate herbivores (nitrogen, organic matter, neutral detergent fiber, acid detergent fiber, lignin, neutral starch, water-soluble carbohydrates, and in vitro dry matter digestibility). The oblique echoes are believed to arise mainly from ionospheric structures associated with the complex crustal magnetic fields of Mars. Study of triacontyl-functionalized monolithic silica capillary column for reversed-phase capillary liquid chromatography.

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Functional changes in sarcoplasmic reticulum and mitochondria of diseased muscle. Sample preconcentration with chemical derivatization in capillary can you drink alcohol while taking lexapro medicine electrophoresis. Nanoscience under glass: the versatile chemistry of silica nanostructures. Crowding bars, separated by a width of 1 optotype, and the original pilot-testing protocol in the Amblyopia Treatment Study were used to quantify visual acuity. The mutant analysis also indicates that even a low level of interaction with PP2A is sufficient to initiate the E4orf4 apoptotic pathway. Endoscopy is commonly performed in the diagnosis of children with inflammatory bowel disease (IBD). Adverse drug reactions in hospital in-patients: a prospective analysis of 3695 patient-episodes. Nuclear ING2 expression is reduced in human cutaneous melanomas.

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