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Aldezol (Metronidazole)

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Aldezol eliminates bacteria and other microorganisms that cause infections of the reproductive system, gastrointestinal tract, skin, vagina, and other areas of the body. Antibiotics will not work for colds, flu, or other viral infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Other names for this medication:
Aldezole, Anabact, Anaeromet, Avidal, Biozyl, Deflamon, Dumozol, Elyzol, Flagenase, Flagolin, Flanizol, Ginerella, Gynoplix, Imizine, Klont, Lindoplus, Menilet, Metris, Metrogyl, Metrol, Metronid, Metronidazolum, Metronour, Metrosept, Metrovax, Nalox, Nidazyl, Orvagil, Otrozol, Patryl, Promuba, Rozagel, Rupezol, Suanatem, Torgyl, Trichazole, Trichodazol, Trogyl, Vagizol, Venogyl, Vertisal, Zobacide

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Avapro, Soma, Imdur, Dostinex, Neoral, Benemid, Imovane, Pyridium, Riazole, Nimucet, Fiambutol, Pentorex, Evalon, Almpose, Cosaben, Clomip,

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Also known as: Metronidazole


Metronidazole is used to treat bacterial infections in different areas of the body. The extended-release tablets are used to treat women with vaginal infections (bacterial vaginosis).

Metronidazole belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain metronidazole. It may not be specific to Aldezol. Please read with care.

Use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

This medicine is to be used only in the vagina. Use it at bedtime, unless your doctor tells you otherwise.

Do not get it into your eyes, nose, mouth, or skin. If this medicine does get into your eyes, wash them out right away with large amounts of cool tap water. If your eyes still burn or are painful, check with your doctor.

This medicine comes with a patient information leaflet and patient instructions. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Wash your hands with soap and water before and after using this medicine.

Nuvessa™ is available inside a prefilled applicator. The applicator is open at one end where you will insert the plunger and has a pink cap on the other end where the medicine will come out.

Vandazole® is in a tube. You will use an applicator to put the gel into your vagina. The applicator has a plastic tube called a barrel that is open at one end and has a plunger (another piece of plastic that can move inside the barrel) at the other end.

To use the medicine:

To fill the applicator: For cream or gel dosage forms: Nuvessa™: With the pink cap still on, push the tip of the plunger into the open end of the prefilled applicator. Pull the cap off before you insert the applicator into your vagina. Vandazole®: Break the metal seal at the opening of the tube by using the point on the top of the cap. Screw the applicator onto the tube. Squeeze the medicine into the applicator slowly until it is full. Remove the applicator from the tube. Replace the cap on the tube. For vaginal tablet dosage form: Place the vaginal tablet into the applicator. Wet the vaginal tablet with water for a few seconds. To insert vaginal metronidazole using the applicator: For all dosage forms: Relax while lying on your back with your knees bent (or in any position that you feel comfortable). Hold the full applicator in one hand. Insert it slowly into the vagina. Stop before it becomes uncomfortable. Slowly press the plunger until it stops. Withdraw the applicator. The medicine will be left behind in the vagina. Remove the applicator from your vagina. Use each applicator only once, and then throw it away.

To help clear up your infection completely, it is very important that you keep using this medicine for the full time of treatment, even if your symptoms begin to clear up after a few days. If you stop using this medicine too soon, your symptoms may return. Do not miss any doses. Also, continue using this medicine even if your menstrual period starts during the time of treatment.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For bacterial vaginal infections: For vaginal dosage form (cream): Adults—One applicatorful (500 milligrams [mg]), inserted into the vagina. Use the medicine 1 or 2 times a day for 10 or 20 days. Children—Use and dose must be determined by your doctor. For vaginal dosage form (gel): Nuvessa™: Adults and children 12 years of age and older—One applicatorful (5 grams [g]) inserted into the vagina once (at bedtime). Each applicatorful of Nuvessa™ contains 65 mg of metronidazole. Children younger than 12 years of age—Use and dose must be determined by your doctor. Vandazole®: Adults—One applicatorful (5 grams [g]) inserted into the vagina once a day (at bedtime) for 5 days. Each applicatorful of Vandazole® contains 37.5 mg of metronidazole. Children—Use and dose must be determined by your doctor. For vaginal dosage form (tablets): Adults—One 500 milligram (mg) tablet, inserted high into the vagina. Use the medicine once a day in the evening for 10 or 20 days. Children—Use and dose must be determined by your doctor.


Single oral doses of Aldezol, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Aldezol has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Aldezol overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.


Store below 77 degrees F (25 degrees C) and protect from light.

Side effects

The most common side effects associated with Aldezol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


To reduce the development of drug-resistant bac- teria and maintain the effectiveness of Aldezol and other antibacterial drugs, Aldezol should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

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To identify the educational needs of HCPs working in LTCF with regard to pain management. Effects of altering dosing on cationic liposome-mediated gene transfer to the respiratory epithelium. The broad coexpression phenomenon was observed both in crypts and villi as demonstrated by immunohistochemistry and FACS analysis of separated cell populations. In the last decade, several papers have appeared in the literature reporting the self-administration of various substances into a number of brain regions. The initial immune process that triggers autoimmune beta cell destruction in type 1 diabetes is not fully understood. Evolving trends in critical care nursing practice: results of a certification role delineation study. Inhibition of excitatory neurotransmitter-nitric oxide signaling pathway by inhalational anesthetics.

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The major components of the acidic fraction glycolipids were characterized as the lactose-based gangliosides Glac1 (GM3) and Glac2 (GD3). Current commonly employed morphologic approaches result largely in subjective findings difficult to analyze statistically and often are directed at levels of structural organization inconsistent with biochemical and physiological approaches. Consistently, the synthetic peptides PTX3-(82-110) and PTX3-(97-110) bind FGF2 and inhibit the interaction of FGF2 with PTX3 immobilized to a BIAcore sensor chip, FGF2-dependent EC proliferation, and angiogenesis in vivo. In exposed workers, bone lead level predicted lower current cognitive performance and cognitive decline over 22 years. The Central Medical Unit (CMU)--a freestanding primary care medical clinic staffed by physicians and nurse practitioners. To improve the efficacy of medical treatment of patients with lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH), studies on combination treatment with alpha(1)-blockers and 5alpha-reductase inhibitors, alpha(1)-blockers and muscarinic receptor antagonists, and alpha(1)-blockers and 5-phosphodiesterase inhibitors are increasingly performed. Membrane-perturbing properties of three peptides corresponding to the ectodomain of hepatitis C virus E2 envelope protein.

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As a first step, we examined the effects of these three transmitters on the identified inhibitory interneuron RP14 in isolated pleural-pedal ganglia. Insect vectors, primarily leafhoppers, planthoppers, and psyllids, have been identified for relatively few phytoplasma diseases, limiting the capacity of managers to make informed decisions to protect crops and endangered indigenous plants. In nearly all cases, the glandular epithelial cells in the endometrium showed expression of alpha (2-), alpha (3)-, alpha (6)- and alpha (v)- integrin and a low percentage of expression of alpha (1)-, alpha (4)-, and alpha (5)-integrin. Three-dimensional ultrasound can be of value in the prenatal diagnosis of such deformities. This link between bladder cancer in women and occupational factors has received little recognition, probably because studies addressing these issues have predominantly been done in men. The angiopoietin/Tie2 system has been identified as the second vascular-specific receptor tyrosine kinase system controlling vessel assembly, maturation, and quiescence. Both genetic and environmental risk factors are involved in the development of CMM.

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Despite this, AgRP-deficient mice were recently reported to exhibit normal food intake, body weight gain, and energy expenditure. Our objective was to determine the influence of the gadolinium-based MRI contrast media on histamine release from mast cells and to compare the activity of ionic and non-ionic preparations of contrast media. The Person-Environment-Occupation Model is offered as a tool for therapists to use in client(s)-therapist alliances to enable clients to successfully engage in meaningful occupations in chosen environments. In the model, a hypothetical population of 100,000 persons aged 50 years underwent colorectal screening every 10 years. 147,290 patients had different drugs for thromboembolism prophylaxis. Participation of ATP/ADP antiporter in oleate- and oleate hydroperoxide-induced uncoupling suppressed by GDP and carboxyatractylate. These interferon components were purified to a specific activity of 3 X 10(7) to 4 X 10(7) units/mg protein by antibody affinity chromatography and examined by electrophoresis in SDS-polyacrylamide gels. In the absence of an ideal vaccine for VL, control measures would essentially include prevention of transmission through vector control and community awareness. Discriminating the molecular pathways during uptake and release on nanoporous host systems.

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Multiple inhibitory receptors that regulate NK-cell cytotoxicity have been characterized whereas little is known about receptors regulating cytokine production. However, there are a number of reasons to believe that spontaneous neoplasms are derived from large numbers of cells. Reprofiling a classical anthelmintic, pyrvinium pamoate, as an anti-cancer drug targeting mitochondrial respiration. Using rat acinar cell cultures, we studied the role of Notch signaling in a model of acinar-to-beta-cell conversion. Further, it poses the question of whether BCG immunization of humans alters resistance to unrelated pathogens. This study investigates specific beliefs related to prevention of AIDS and HIV infection among African-American teenagers. A family of putative receptor-adenylate cyclases from Leishmania donovani. Comparing the effect of topical application of human milk and dry cord care on umbilical cord separation time in healthy newborn infants. The researchers used a nested case-control study to compare serum isoflavones (daidzein, genistein, glycitein, and equol) levels between 165 participants that died or were certificated as disabled (cases) and 177 controls. Certain disease states may be accompanied by still higher vitamin C requirements but the exact amounts are not yet known.

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Tissue-selective expression of dominant-negative proteins for the regulation of vascular smooth muscle cell proliferation. Changes in protein kinase C and its presynaptic substrate B-50/GAP-43 after intrauterine exposure to methylazoxy-methanol, a treatment inducing cortical and hippocampal damage and cognitive deficit in rats. Head and Neck Cancer Control Network completes five years in Wisconsin. Antidesmosomal monoclonal antibody in the diagnosis of intracranial tumours. FDG PET-CT is a useful imaging modality in differential diagnosis of malignant and benign pleural lesions. Evidence for early loading of osseointegrated implants for bone conduction at 4 weeks.

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There are apparent differences in clinicopathological features and prognosis between LHCDD and LCDD. The condition improved with PSL and cyclophosphamide administration. The aim of this study was to assess the feasibility and the technical aspects of robotic-assisted laparoscopic cholecystojejunostomy. -- Therefore a multiphasic screening was carried out in 5,424 persons at the age of 20 and more years, which tested the problems mentioned and judged the possibilities of an improved diagnosis. Likewise, the LPAAT activity associated with CtBP/BARS is also a co-purification artefact. Regression of abdominal aortic aneurysm by inhibition of c-Jun N-terminal kinase. Immunohistochemical localization of leucine-rich proteoglycans in the developing periodontal tissues of mice. The growth-inhibitory effect of cefmenoxime against Proteus vulgaris was studied by using the broth dilution and paper disk diffusion methods. A heated indium tin oxide (ITO) electrochemiluminescent (ECL) cell containing an ITO counter electrode, an ITO reference electrode, and a heated ITO working electrode has been fabricated to promote ionic liquid (IL)-mediated ECL reactions and hence improve sensitivities of IL-based ECL sensors. Three patients with acute HCV infection had a normal clinical course, but the remaining patient had severe disease with ascites and a marked decrease in prothrombin activity.

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The pattern of Sulf1 expression in the peri-mesenchymal epithelium matched predicted locations of bone morphogenetic protein (BMP) signaling. Most pediatric patients with CM do not appear to be at risk of widespread mast cell degranulation during anesthesia but because of the small number of cases reported, the risk cannot be ascertained with confidence. We have annotated 29,556 different sequences, an almost 5-fold increase in annotated sequences compared to the available wheat public databases. The formation of milia is well recognized in both bullous and inflammatory dermatoses. Patterns of morphological variation within myelin internodes of normal peripheral nerve: quantitative analysis by confocal microscopy. Stress induced in heart and other tissues by rat dermal exposure to JP-8 fuel. In addition, the highest specific IPA degradation rate was obtained at a concentration of 7.5 g l(-1) with a corresponding value of 0.045 g IPA g cells(-1) h(-1). To assess genetic variation among GAS in western Nepal, 120 noninvasive GAS, collected from eight different villages, were genetically characterized using emm typing, sof sequencing, and multilocus sequence typing (MLST). We conclude that Mlc is a repressor for the pts transcription acting as a major regulatory protein involved in the glucose induction of pts operon. The resulting thioredoxin-targeted nanodevice was found to bind selectively to certain cell lines but not to others.

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A case of Churg-Strauss syndrome in which oculomotor paralysis developed. Histologically, the re-operated mediastinal tumor was of tuberculous lymphadenitis. Although it may not be common, compression of the sacral plexus caused by dynamic motion of the obturator internus muscle should be included as a possible diagnosis for sciatic pain. Effects of sodium taurodihydrofusidate on nasal absorption of insulin in sheep. The expression level of EIG121 was then measured by real-time quantitative reverse transcription-PCR in benign, hyperplastic, and malignant endometrial samples. The scope of this new atom-economic process is described herein. The aim of this article is to review the basic principles, instrumentation, applications, and potential problems related to endoscopic ultrasound and to attempt to define the realistic role for this tool in contemporary medical practice.

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P-gp expression and/or activity has been associated with unfavourable outcome in paediatric ALL patients, whereas MRP1 and BCRP do not seem to play a major role. An arrhythmia specialist and a cardiac genetic service should be involved early, with storage of DNA and cardiac/genetic investigation of the family. 2nd communication: tissue distribution study of a lyophilized purified human activated protein C after single or repeated metoclopramide 10 mg inj intravenous administration in male mice and placental transfer and milk passage study after intravenous administration in pregnant and lactating mice. A retrospective review of 88 patients who underwent RPLND for Stage I or II NSGCTs between 1971 and 1991 was performed to determine the incidence and site of any retroperitoneal recurrence. The content validity and cultural relevancy of this scale were examined by experienced researchers, mental health professionals and mental health consumers which resulted in the 17-item Psychosocial Treatment Compliance Scale (PTCS). Interference in the vaccination of cattle against rinderpest virus by antibodies against peste des petits ruminants (PPR) virus. The 2,6-diaminopurine Z-prodrug seems to be the best candidate for further development. Recent studies suggest that several proinflammatory mediators participate in lesion development. Swampscott Anniversary Symposium: reflections and recommendations on the 20th anniversary of Swampscott.

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One mechanism by which glucose might act on memory and other brain functions is by regulating the ATP-sensitive potassium channel. Consequently, they impact different developmental programmes responsible for the changes in root system architecture under differential Pi supply. Maternal blood, liver, kidney, and placental and fetal (embryo) accumulation of cadmium (Cd), a known embryotoxic trace element, was investigated following a single oral dose of various amounts of Cd (10 to 1,000 microgram/rat) as CdCl2 containing 109Cd at days 6, 10, 14, and 17 of gestation. Antioxidant and antibacterial activities of Rumex japonicus HOUTT. We studied SSD and its allometry among 74 breeds ranging in height from less than 19 cm in Chihuahua to about 84 cm in Irish wolfhound. Quality of life in chronic kidney failure patients receiving hemodialysis treatment. Using Google Analytics to evaluate the impact of the CyberTraining project.

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High Court quashes GMC suspension of consultant for carrying phial of blood in hand luggage. Furthermore, we find that Rictor is a haploinsufficient gene and that deleting one copy protects Pten heterozygous mice from prostate cancer. Behavioral research has demonstrated three major components of the lexical-semantic processing system: automatic activation of semantic representations, strategic retrieval of semantic representations, and inhibition of competitors. Expression of SRIF mRNA in the PeN of the hypothalamus was monitored bactrim dose kids by in situ hybridization and relative levels were determined with an image analysis system. We hypothesized that different populations of copepods may deal differently with the same oxylipin-producing diatom diet.

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The organization of mitochondrial atp6 gene region in male fertile and CMS lines of pepper (Capsicum annuum L.). The process of stone formation within the urinary tract involves multiple etiologic factors. Four main themes relating to the course structure in teaching creativity were developed: diversity learning, freedom to learn, learning with confidence and learning through group work. Sex of the cell dictates its response: differential gene expression and sensitivity to cell death inducing stress in male and female cells. Alongside traditional clinical and biological techniques, molecular biological methods have gained a broad scope of application and will be used even more frequently in the future. Starting from a description of the advantages and weaknesses of the Minnesota multiphasic personality inventory (MMPI) test, the authors discuss the development, standardization, and normalization of an abbreviated form (DKO/74) which is used in Poland. Conceptually, GNs are (un)directed graphs, where the nodes correspond to the genes and a link between a pair of genes denotes a regulatory interaction that occurs at transcriptional level. An exaggerated systolic blood pressure response to exercise is associated with cardiovascular remodeling in subjects with prehypertension. The mechanisms that lead to centrosome abnormalities such as centrosome hyperamplification and multipolarity in response to DNA damage will also be addressed. This latter effect illustrates the strategic adaptation of group behavior to audience (i.e., displaying in-group bias may provoke the out-group and be counterproductive in instrumental terms).

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