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Agiclob (Clobetasol)

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Agiclob is a very strong steroid medication used on the skin to relieve inflammation and itching caused by certain skin conditions. Generally, it should only be used for a maximum of two weeks at a time to prevent thinning of the skin and other side effects.

Other names for this medication:
Betalic, Betanate, Clobadis, Clobate, Clobesym, Clobetamil, Clobetasol, Clobevate, Clobezine, Clobin, Clomad, Clomic, Clonate, Clotof, Clovate, Cosvate, Cutivate, Cvate, Eavone, Ecziclo, Embeline, Etavone, Gracederm, Isovate, Kloryl, Klosol, Lobate, Magclo, Miconit, Salyco, Sonaderm, Steriderm, Steridom, Taxalic, Tigerderm, Topifort, Zincoderm

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Also known as: Clobetasol


Clobetasol is a highly potent steroid that helps reduce inflammation in the body.

Agiclob (for the skin) is used to treat inflammation and itching caused by plaque psoriasis or skin conditions that respond to steroid medication.


This section provides information on the proper use of a number of products that contain clobetasol. It may not be specific to Agiclob E. Please read with care.

It is very important that you use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects or skin irritation.

This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

This medicine is for use on the skin only. Do not get it into your eyes, nose, mouth, or vagina. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water.

To help clear up your skin or scalp problem completely, it is very important that you keep using this medicine for the full time of treatment. Do not miss any doses.

This medicine should only be used for skin conditions that your doctor is treating. Check with your doctor first before using it for other conditions, especially if you think that a skin infection may be present. This medicine should not be used to treat certain kinds of skin infections or conditions, such as severe burns.

Do not use this medicine on the face, groin, or underarms, or if you have skin thinning, unless directed to do so by your doctor.

To use the cream, foam, gel, lotion, ointment, or spray:

Wash your hands with soap and water before and after using this medicine. Apply or spray a thin layer of this medicine to the affected area of the skin. Rub it in gently. With the lotion, protect the skin from water, clothing, or anything that causes rubbing until the medicine has dried. Also, shake the lotion well before using it. With the foam, do not dispense directly from the can into your hands, unless the hands are the affected area. Do not bandage or otherwise wrap the skin being treated unless directed to do so by your doctor. Do not use Clobex® spray or Impoyz™ cream for more than 2 weeks unless your doctor told you to.

To use the foam, scalp solution, or shampoo:

Wash your hands with soap and water before and after using this medicine. Apply a thin layer of this medicine to the affected area of the scalp. Rub it in gently. Do not cover the scalp (eg, shower cap, bathing cap) while it is being treated. With the shampoo, do not wet your hair before using it. And if the shampoo gets on any part of your body other than your scalp, rinse the area well with water. Do not use the shampoo for more than 4 weeks, and the foam and scalp solution for more than 2 weeks unless your doctor told you to.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For redness, itching, and swelling of the skin: For topical dosage forms (cream, gel, or ointment): Adults—Apply to the affected area of the skin 2 times per day. Children 12 to 17 years of age—Apply to the affected area of the skin 2 times per day. Children younger than 12 years of age—Use is not recommended. For topical dosage form (lotion): Adults—Apply to the affected area of the skin 2 times per day. Children—Use is not recommended. For plaque psoriasis: For topical dosage form (cream): Impoyz™: Adults—Apply to the affected area of the skin 2 times per day. Children—Use is not recommended. Agiclob®: Adults and children older than 16 years of age—Apply to the affected area of the skin 2 times per day. Children younger than 16 years of age—Use is not recommended. For topical dosage form (foam): Adults—Apply to the affected area of the skin 2 times per day, once in the morning and once at night. Children 12 to 17 years of age—Apply to the affected area of the skin 2 times per day, once in the morning and once at night. Children younger than 12 years of age—Use is not recommended. For topical dosage form (spray): Adults—Spray directly to the affected area of the skin 2 times per day. Children—Use is not recommended. For scalp problems: For topical dosage forms (foam or scalp solution): Adults—Apply to the affected area of the scalp 2 times per day, once in the morning and once at night. Children 12 to 17 years of age—Apply to the affected area of the scalp 2 times per day, once in the morning and once at night. Children younger than 12 years of age—Use is not recommended. For topical dosage form (shampoo): Adults—Apply to the affected area of the scalp once a day. Children—Use is not recommended.


Generic Agiclob is not expected to cause overdose symptoms. But long-term use of high Generic Agiclob doses can lead to symptoms such as: thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Agiclob are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Agiclob if you are allergic to it.

Tell your doctor if you have ever had:

any type of skin infection; a skin reaction to any steroid medicine; liver disease; or an adrenal gland disorder.

Steroid medicines can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes.

It is not known whether Agiclob will harm an unborn baby. Tell your doctor if you are pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. If you apply clobetasol to your chest, avoid areas that may come into contact with the baby's mouth.

Agiclob is not approved for use by anyone younger than 12 years old. Some brands or forms of this medicine are for use only in adults 18 and over.

Children can absorb larger amounts of this medicine through the skin and may be more likely to have side effects.

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