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Acupain (Tramadol)

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Acupain is used to relieve moderate to moderately severe pain. Acupain is in a class of medications called opiate (narcotic) analgesics. It works by changing the way the brain and nervous system respond to pain.

Other names for this medication:
Acema, Decotram, Dolodol, Dolotram, Domaspas, Formador, Ibudol, Leedol, Midol, Nopidol, Ondol, Opidol, Oshdol, Paxmax, Radol, Rimol, Sedate, Spasteez, Supridol, Tandam, Tradol, Tramadol, Tramafen, Tramak, Trampar, Trandol, Tromfil, Trydol, Ubitdol, Ultrax, Unidol, Urogendo, Vardol, Vintram, Xtram

Similar Products:
Lamictal, Abhigra, Zocor, Hytrin, Anafranil, Alprostadil, Eriacta, Eulexin, Etorvel, Avispas, Pantonid, Daomet, Nuroflow, Fexoriv,

Also known as: Tramadol


Acupain ER is an pain medicine similar to an opioid. This medicine is used to treat moderate to severe pain.

The extended-release form of tramadol is for around-the-clock treatment of pain. This form of tramadol is not for use on an as-needed basis for pain.


Follow the directions on your prescription label and read all medication guides. Never use Acupain ER in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to take more of Acupain ER.

Never share Acupain ER with another person, especially someone with a history of drug addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law.

Stop taking all other opioid medications when you start taking Acupain ER.

Acupain ER can be taken with or without food, but take it the same way each time.

Swallow the capsule or tablet whole to avoid exposure to a potentially fatal overdose. Do not crush, chew, break, open, or dissolve.

Measure liquid medicine with the supplied syringe or a dose-measuring device (not a kitchen spoon).

Never crush or break a Acupain ER pill to inhale the powder or mix it into a liquid to inject the drug into your vein. This practice has resulted in death.

You may have withdrawal symptoms if you stop using Acupain ER suddenly. Ask your doctor before stopping the medicine.

Store at room temperature away from moisture and heat. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.

Do not keep leftover Acupain ER. Just one dose can cause death in someone using it accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, mix the leftover medicine with cat litter or coffee grounds in a sealed plastic bag throw the bag in the trash.

Detailed Acupain ER dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Keep your tablets in the blister pack until it is time to take them. If you take the tablets out of the blister pack they may not keep well.

Keep the medicine in a cool, dry place where the temperature stays below 25 degrees C.

Do not store it or any other medicine in the bathroom, near a sink or on windowsill.

Do not leave it in the car. Heat and damp can destroy some medicines.

Keep it where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

Side effects

The most common side effects associated with Acupain are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Acupain if you are allergic to tramadol, or if you have:

severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine).

Acupain should not be given to a child younger than 12 years old. Acupain ER should not be given to anyone younger than 18 years old.

Do not give Acupain to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Seizures have occurred in some people taking Acupain. Your seizure risk may be higher if you have ever had:

a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder.

To make sure Acupain is safe for you, tell your doctor if you have ever had:

breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt.

If you use tramadol during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor before using tramadol if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

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Lower oesophageal sphincter pressure (LOSP) has been measured on three separate occasions in nine healthy volunteers using oesophageal pressure transducers. Results indicate that cathodal stimulation acutely degraded attentional switches during stimulation, and anodal stimulation persistently degraded local-to-global attentional switching for at least 20 min after stimulation. This study demonstrated that administration of crocetin to experimental animals during resuscitation from shock significantly improved postshock survival and reduced apoptosis. The incidence of Fallopian canal dehiscence was significantly higher in temporal bones from donors older than 18 years with chronic middle ear disease. The results of the this study suggest that elemental diets stimulate the duodental mucosa to secrete cholecystokinin which stimulates the exocrine pancreas. We performed a retrospective analysis of adult patients, from the 2013 to 2014 American College of Surgeons Trauma Quality Improvement Program (TQIP) Participant Use Data Files, who sustained grade IV or V BSI. Death of marine teleosts from DDT poisoning probably involves factors other than simply osmoregulatory failure. After the objectives of the database approach have been defined, the major components of databases and their function will be discussed. Taking into account the x-ray crystal structure for FKBP51, we conclude that the C-terminal regions of FKBP51 and FKBP52 outside the core TPR domains are likely to assume alternative conformations that significantly impact Hsp90 binding. Alteration in directional sensitivity of the retina by monocular occlusion.

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Genetic variation has been the mainstay of hematopoietic stem cell transplantation since the first transplants were attempted. It is given by the Fredholm determinant of the counting operator with a time-dependent scattering phase. Two saliency cues, intensity and compactness, are then proposed for the estimation of the saliency map of each individual superpixel at each level. Formation of secretory granules in pancreatic islet B cells of cortisone-treated rabbits. This article presents a near real-time processing solution using MapReduce and Hadoop. zeylanica extract possesses peripheral analgesic and mild antipyretic effects and its major constituent, strictosidinic acid, exerts a similar analgesic effect with marked antipyretic activity.

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