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Actizide (Glipizide)

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Actizide works by increasing the amount of insulin your body produces (in the pancreas). The insulin then works to lower your blood glucose level. It is usually taken once a day. You should keep taking it for as long as it is prescribed.

Other names for this medication:
Actizide, Bimode, Diabizide, Diacon, Diaglip, Dibimet, Dibizide, Glanase, Glibetic, Glicept, Glimet, Glipicon, Glipicontin, Glipid, Glipimet, Glipiriv, Glipitis, Glipixor, Glipized, Glipizide, Glipmet, Glucolip, Gluconil, Glumin, Glunas, Glycind, Glydal, Glylin, Glynase, Glysar, Glysin, Glyson, Glytop, Glyzip, Gpzide, Libiz, Metaglez, Metglib, Swiglip, Tranase, Zidmin

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Also known as: Glipizide


Actizide is a medication consists in a class of drugs called sulfonylureas. Actizide is used to treat type 2 diabetes. Actizide may be used along with diet, exercise and insulin therapy. Actizide is also known as Glipizide, Glytop SR. Actizide works by controlling blood sugar levels in your organism. Generic name of Actizide is Glipizide. Brand names of Actizide are Actizide, Actizide XL.


Usual Adult Dose of Actizide for Diabetes Type 2:

Immediate release: Initial dose: 5 mg orally once a day, 30 minutes before breakfast Maintenance dose: Up to 40 mg in divided doses 30 minutes before a meal of adequate caloric content. Doses may be increased in intervals of 2.5 to 5 mg a day according to blood glucose response. Maximum single dose: 15 mg Maximum daily dose: 40 mg Comments: -At least several days should elapse between titration steps. -If response to a single dose is not satisfactory, dividing that dose may prove effective. Extended Release: Initial dose: 5 mg orally once a day, 30 minutes before breakfast Maintenance dose: 5 to 10 mg orally once a day Maximum daily dose: 20 mg Patients receiving immediate release may be switched safely to extended release tablets once-a-day at the nearest equivalent total daily dose, or titrate to the appropriate extended release dose starting with 5 mg once daily. Combination use: -When adding other blood-glucose-lowering agents to the extended release tablets, the agent should be initiated at the lowest recommended dose. Observe for hypoglycemia. -When adding extended release tablets to other blood-glucose-lowering agents, Actizide XL extended release can be initiated at 5 mg. Start at a lower dose in patients that are more sensitive to hypoglycemia. When transferring patients from insulin to glipizide, the following general guidelines should be considered: -For patients with daily insulin doses of 20 units or less: Discontinue insulin and begin glipizide at usual dosages. -For patients with daily insulin doses greater than 20 units: Insulin dose should be reduced by 50% and glipizide therapy may begin at usual dosages. Comments: -Several days should elapse between titration steps. -Subsequent reductions in insulin dosage should depend on individual patient response. -During the insulin withdrawal period, the patient should test urine samples for sugar and ketone bodies at least three times daily. -Some patients receiving greater than 40 units of insulin daily may need to consider hospitalization during the transition period. Patients Receiving Other Oral Hypoglycemic Agents: -When transferring from longer half-life sulfonylureas: Observe for 1 to 2 weeks for hypoglycemia. -Actizide XL extended release coadministered with colesevelam: Glipizide should be administered at least 4 hours prior to colesevelam. Use: Adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Usual Geriatric Dose of Actizide for Diabetes Type 2:

Initial dose: 2.5 mg orally once a day 30 minutes before breakfast Comments: -Maintenance dosing should be conservative to avoid hypoglycemic reactions. -Doses can be adjusted with caution taking into account the degree of hepatic, renal, or cardiac function, and the concomitant disease or other drug therapy. Use: Adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Detailed Actizide dosage information


If you overdose Actizide and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Actizide overdosage: hunger, nausea, anxiety, cold sweats, weakness, drowsiness, unconsciousness, coma.


Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Actizide are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of glipizide in the pediatric population. Safety and efficacy have not been established.

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Maladaptive immune responses are considered to be important factors in the pathogenesis of the two diseases caused by hantaviruses, hemorrhagic fever with renal syndrome and hantavirus cardiopulmonary syndrome (HCPS). Instances of intergenotype recombination were observed in all human and ape HBV variants, including evidence for a novel gibbon/genotype C recombinant among HBV variants from Vietnam. The length of the CAG repeat sequence in the IT15 gene and the adjacent CCG and Delta2642 polymorphisms were determined by polymerase chain reaction along with common genotypes of the angiotensin-converting enzyme (ACE) and apolipoprotein E (APOE) genes. However, other species such as Pterocarpus santalinoides and Mimosa pigra were not ecotype specific. Continuous surveillance of this sample of 5209 subjects has been maintained through biennial physical examinations. The correlation between modules and exons observed in different proteins suggests that each module was encoded by an ancestral exon and that modules were combined into globular domains by exon fusion. Herpes zoster (HZ) occurs with an increased incidence in immunosuppressed patients, in whom it frequently displays atypical clinical presentations. Extracranial-intracranial arterial bypass in the treatment of aneurysms of the carotid and middle cerebral arteries. Repetitive TASER X26 discharge resulted in adverse physiologic events with a dose-response relationship related to the duration of discharge in anesthetized swine model.

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Laser photocoagulation was indicated to the left and a strict surveillance to the right eye. A plasmalogen, plasmenylethanolamine, is required for in vitro growth of strains of Eubacterium which convert cholesterol to coprostanol. Proteolytic activities in bronchoalveolar lavage fluid of interstitial lung diseases: correlation to stage and prognosis. No immunoprecipitates were detected with these antibodies in lysates from cells grown without EGF. We examined correspondence between preference assessment outcome and within-session patterns of responding in one subject with autism. Self-report of AA meeting attendance and involvement, alcohol consumption (percentage of days abstinent, percentage of days heavy drinking) and negative alcohol consequences. We show that HXR9 causes apoptosis in a number of breast cancer-derived cell lines and that sensitivity to HXR9 is directly related to the averaged expression of HOX genes HOXB1 through to HOXB9, providing a potential biomarker to predict the sensitivity of breast tumors to HXR9 or its derivatives. This contrasts with protein-protein interactions, which have been intensively recorded in public databases and subjected to network level analysis. The Crimea State Medical University is a state higher educational establishment having the 4th highest level of state accreditation.

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Changes observed in plasma LDH-5 after exposure to these agents suggest that, as a result of phagocytosis or cell damage, peritoneal leukocytes contribute to early increases in plasma enzyme activity, whereas extensive liver involvement is responsible for high secondary LDH-5 levels during progressive tularemic infection. The final diagnosis was BPB classified as pathological stage IIB (T3N0M0). Effects of diterpenes isolated from the Brazilian marine alga Dictyota menstrualis on HIV-1 reverse transcriptase. The vasodepressor function of the kidney: prostaglandin E2 is not the principal vasodepressor lipid of the renal medulla. In these latter compartments, CD1e participates in the processing of glycolipid antigens. Biosynthesis of phosphatidic acid by liver and lung of maternal and fetal rabbits. The use of the immunosuppressive agent sirolimus (SRL) has been associated with a significant increase in lymphocele formation.

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The cellular distribution of osteoclast integrin subunits alpha(v) and beta(3), the tissue distribution, and level of the apparent ligand osteopontin (OPN) as well as of the putative regulatory enzyme tartrate-resistant acid phosphatase (TRAP) were studied along with the intracellular distribution of the activation marker c-src in osteopetrotic ia/ia (incisors-absent) mutant rats and their normal littermates. Reexcision rate was reduced with the use of frozen section analysis. Spermiogenesis has shown the presence of some interspecific variations among Chelonia, while the general features of the testes and spermatocytes are morphologically similar to other reptilians. Synthetic retinoids have been particularly useful for prevention of bladder and breast cancer in experimental animals. Expression patterns of arginase, soluble guanylyl cyclase and cyclic nucleotide phosphodiesterase revealed striking parallels with that of NO synthase (NOS). To evaluate the utility and efficacy of perfluoroperhydrophenanthrene in the management of retinal detachments secondary to severe proliferative diabetic retinopathy. The deposition of talc in patients with silicone gel-filled breast implants. The responses were converted to a rating of excellent, good, fair, poor, or unacceptable for each component. Clinicians should consider orthodontic movement of endodontically treated teeth as a relatively safe clinical procedure. In the second coronary angiography we investigated whether they had a new culprit lesion clearly differentiated from the rhinocort aqua dosage one of the first angiogram.

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