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Abilify

Abilify is an inexpensive drug used to treat schizophrenia and bipolar disorder, also known as manic-depression. It is also used to treat Tourette's disorder and some symptoms of autism. Abilify may also be used in combination with antidepressants to treat major depressive disorder. This drug is slightly more popular than comparable drugs. It is available in brand and generic versions.

Other names for this medication:
Apicord, Aridus, Arifril, Arilan, Arinex, Aripat, Aripicon, Aripiprazole, Aripra, Arpicin, Asprito, Biliff, Elrip, Pipra, Rizotal, Schizopra

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Also known as: Aripiprazole

Description

Aripiprazole injection is used to treat agitation caused by schizophrenia or bipolar mania.

Aripiprazole extended-release injection is used to treat schizophrenia (a mental disorder) and bipolar disorder (manic-depressive illness). It works in the brain to change how certain chemicals affect patients. Aripiprazole is an antipsychotic agent.

This medicine is to be given only by or under the immediate supervision of your doctor.

Dosage

This section provides information on the proper use of a number of products that contain aripiprazole. It may not be specific to Abilify Discmelt. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not open the blister pack that contains the tablet until you are ready to take it. Remove the tablet from the blister pack by peeling back the foil, then taking the tablet out. Do not push the tablet through the foil. Do not break or split the tablet. Place the tablet in your mouth. It should melt quickly. After the tablet has melted, you may swallow or take a sip of water.

Swallow the tablets whole. Do not break, crush, or chew them.

Abilify Mycite® has a sensor in the tablet, which helps track it inside the stomach or bowels. The Abilify Mycite® System comes with a patch (wearable sensor), a smartphone application (app), and a web-based portal. Follow your doctor's instructions on how to use the medicine.

The Abilify Mycite® tablet is usually detected within 30 minutes after you take it, but there may be a delay of more than 2 hours for the smartphone app and web portal to detect that you have taken the medicine, and sometimes it might not be detected at all.

To apply the Abilify Mycite® patch:

The app will tell you when to apply or remove the patch. It should be changed weekly or sooner as needed. Place the patch to the left side of your body just above the lower edge of your rib cage. Do not put the patch in areas where the skin is scraped, cracked, inflamed, or irritated, or near the area where you had removed the previous patch. The app will help you place the patch in the correct location. You may keep the patch on when showering, swimming, or exercising.

Aripiprazole may be taken with or without food. If your doctor tells you to take it a certain way, follow your doctor's instructions.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (tablets and orally disintegrating tablets): For bipolar mania: Abilify® and Abilify Discmelt®: Adults—At first, 15 milligrams (mg) once a day. When it is given with lithium or valproate, the starting dose is 10 to 15 mg once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children 10 years of age and older—At first, 2 mg once a day. The dose will be gradually increased to 10 mg once a day. Your doctor may adjust your dose again as needed. However, the dose is usually not more than 30 mg per day. Children younger than 10 years of age—Use and dose must be determined by your doctor. Abilify Mycite®: Adults—At first, 15 milligrams (mg) once a day. When it is given with lithium or valproate, the starting dose is 10 to 15 mg once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children—Use and dose must be determined by your doctor. For depression: Adults—At first, 2 to 5 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 15 mg per day. Children—Use and dose must be determined by your doctor. For irritability in children with autistic disorder: Children 6 to 17 years of age—At first, 2 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 15 mg per day. Children younger than 6 years of age—Use and dose must be determined by your doctor. For schizophrenia: Abilify® and Abilify Discmelt®: Adults—At first, 10 to 15 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children 13 to 17 years of age—At first, 2 mg once a day. The dose will be gradually increased to 10 mg once a day. Your doctor may adjust your dose again as needed. However, the dose is usually not more than 30 mg per day. Children younger than 13 years of age—Use and dose must be determined by your doctor. Abilify Mycite®: Adults—At first, 10 to 15 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children—Use and dose must be determined by your doctor. For Tourette's disorder: Children 6 to 18 years of age—At first, 2 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 20 mg per day. Children younger than 6 years of age—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include drowsiness, vomiting, aggression, confusion, tremors, fast or slow heart rate, seizure (convulsions), weak or shallow breathing, or fainting.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Abilify Discmelt dosage information

Side effects

The most common side effects associated with Abilify are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies have not been performed on the relationship of age to the effects of aripiprazole injection in the pediatric population. Safety and efficacy have not been established.

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Post-translational inhibition of IP-10 secretion in IEC by probiotic bacteria: impact on chronic inflammation. The gender of the patient and the relationship to the carer are associated with cognitive and functional scores at the time of presentation in patients with dementia. The data underscore the importance of fully-functional translation machinery for efficient cerebral inflammatory response upon insults. The sol-gel transition of these block copolymer solutions was fine-tuned by controlling the PEG length, the hydrophobic to hydrophilic block ratio (PCLA/PEG), and the molecular weight of the sulfamethazine oligomer. The laser sites were randomly left untreated or treated with petroleum-based ointment or dressed with 1 of the following occlusive dressings: hydrocolloid, hydrogel or foam. To support payer decision-making, researchers will need to measure the impact of PGx testing on clinical and economic outcomes and demonstrate the net benefit of PGx testing as compared to usual care.

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Presence, in certain lupus sera, of native anti-desoxyribonucleic acid antibodies. An acidic 14-kDa protein purified in the blowfly, Phormia regina, belongs to the insect pheromone-binding protein superfamily, but unlike other lipophilic ligand-binding proteins in insect or vertebrate chemosensory systems, it was distributed in both taste and olfactory organs. A study of the causes of fetal and neonatal mortality on the obstetric service of Bellevus Hospital. The inventory of treatment risks and chance of complications in root canal therapy. We found that the HMO members with diabetes did not disenroll from the HMO at a higher rate than those without diabetes. Electrochemical control of the interactions of polymers and redox-active surfactants. The risk of being fearful or fearless of falls in older people: an empirical validation. While PSAD is more helpful than PSA and free/total PSA ratio for prediction of organ-confined disease, none of these parameters are significant predictor of pathologic stage for clinically localized prostate cancer. Cell counts on and off the FGF-2 patterns over time demonstrated an increase in cell density up to a FGF-2 surface concentration of 14 pg/mm(2).

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Synthesis and evaluation of apoptosis induction of thienopyrimidine compounds on KRAS and BRAF mutated colorectal cancer cell lines. The Raman peak at 1655 cm(-1), absent in the free anti-CEA spectrum, is the signature of the anti-CEA binding onto the precoated magnetic nanoparticles. 12 LQTS patients were selected to do exercise test (ET) to mimic sympathetic activation. Significant progress has been made in understanding the molecular and cellular albendazole oral suspension ip bandy uses in hindi mechanisms and pathogenesis in lung cancer. No major abnormalities were overlooked during the examination of these patients. Dose enhancement factor (DEF) increased with an increasing concentration of dFdU: DEFs were 1.10, 1.60 and 2.17 after treatment with 10, 25 and 50 microM dFdU, respectively, in ECV304 cells and 1.08, 1.31 and 1.60 after treatment with 25, 50 and 100 microM, respectively, in H292 cells. It was concluded that CD44 gene expression is not the primary target of radioactive irradiation. However, a higher level of physical activity is associated with higher muscle mass and TBK content, and less total and truncal fat. Some implications of this finding for repertory grid assessment and research were discussed.

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Treatment decisions for patients with CML changed over time in routine clinical practice. One such class are the thiazolidinediones (rosiglitazone and pioglitazone). The principal results of EBIIA are a higher diversity of microorganisms isolated in nosocomial infections and decreased susceptibility among these strains. Our results showed that the expression of hADA3 protein was significantly increased, cellular proliferation was decreased and apoptotic rate was increased in SiHa cells treated by E6 siRNA and E6AP siRNA respectively. Urine ratio of tetrahydrocortisol to tetrahydrodeoxycortisol to screen for the systemic administration of cortisone and hydrocortisone. The use of ionising radiation for is mobic stronger than voltaren tablets the treatment of injuries to flexor tendons and supporting ligaments in horses. Analysis of the control swabs, processed alongside the monitoring swabs, has demonstrated that in this environment the risk of forensic sample contamination, assuming all the relevant anti-contamination procedures have been followed, is so small that it is considered to be negligible. Prognostic factors relating to survival in uterine endometrioid carcinoma. Gene prioritization aims at identifying the most promising candidate genes among a large pool of candidates-so as to maximize the yield and biological relevance of further downstream validation experiments and functional studies.

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The majority of reported cases now appear to be of lymphoid cell origin, while few cases of other cancers have been reported to present as APS. We will summarize the literature on the involvement of TGFbeta1 through the Smad proteins in fibrotic diseases. Ten-week-old female Sprague-Dawley rats were exposed to fresh mainstream cigarette smoke or filtered room air twice daily, or maintained as room controls, for 65 weeks. They are active preferentially in the early and late stages of learning, respectively. Ipilimumab, antibody to Programmed death-1 (PD-1), Toll-like receptor agonists, liposomal BLP25 (L- BLP25), belagenpumatucel-L, melanoma-associated antigen A3 (MAGE-A3) vaccine and talactoferrin have been proved to be effective for lung cancer through early clinical trials, most of the xanax drug names drugs have moved forward to phase III trials, so as to collect much higher level evidence to support the immunotherapies incorporated into the multidisciplinary treatment of lung cancer.

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However, epidemiological studies in rural areas are quite rare, especially in Chad. In humans, tropomyosins are encoded by TPM1 (alpha-Tm, 15q22.1), TPM2 (beta-Tm, 9p13.2-p13.1), TPM3 (gamma-Tm, 1q21.2) and TPM4 (delta-Tm, 19p13.1) genes. Impaired renal function portends poor heart failure (HF) outcomes. Second, the effect of co-administration of alpha-adrenoceptor ligands and DOI was evaluated in the same test. Is body size associated with ovarian cancer in southern Chinese women?. Fetal cells in a transcervical cell sample collected at 5 weeks of gestation. Does dexmedetomidine prevent emergence delirium in children after sevoflurane-based general anesthesia?. The HLA-DR data of 75 multigravid women were analysed: the proportion of women who had experienced fetal loss did not how to take maxolon tablets differ between HLA-DR homozygous and heterozygous subjects.

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Acute pancreatitis is an inflammatory disease involving acinar cell injury, and the rapid production and release of inflammatory cytokines, which play a dominant role in local pancreatic inflammation and systemic complications. The first double-blind trial was with twelve patients, ranging from 7-69 years of age, having diseases including the Duchenne, Becker, and the limb-girdle dystrophies, myotonic dystrophy. It is impossible to extrapolate from these observations to human beings. Evidence-based research regarding the bioactivity of this herb is reviewed. The proliferon starts its existence as a whole, matures as a whole and disintegrates at the organ periphery. The rat-pull test procedure: a method for assessing the strength of rats. To analyze reasons for inconclusive results of earlier chloroplast phylogenies in the grass genus Hordeum, we established a genealogy of chloroplast haplotypes by sequencing the trnL-trnF region in 875 individuals, covering all clozapine therapeutic drug monitoring 31 species of the genus.

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